Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults
Abstract. Background:. Evidence on the relations of the American Heart Association's ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained unclear. We aimed to fill the gaps. Methods:. A total of 198,164 partici...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2023-01-01
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| Series: | Chinese Medical Journal |
| Online Access: | http://journals.lww.com/10.1097/CM9.0000000000002379 |
| _version_ | 1797840185281478656 |
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| author | Yanbo Zhang Canqing Yu Shuohua Chen Zhouzheng Tu Mengyi Zheng Jun Lv Guodong Wang Yan Liu Jiaxin Yu Yu Guo Ling Yang Yiping Chen Kunquan Guo Kun Yang Handong Yang Yanfeng Zhou Yiwen Jiang Xiaomin Zhang Meian He Gang Liu Zhengming Chen Tangchun Wu Shouling Wu Liming Li An Pan Jing Ni |
| author_facet | Yanbo Zhang Canqing Yu Shuohua Chen Zhouzheng Tu Mengyi Zheng Jun Lv Guodong Wang Yan Liu Jiaxin Yu Yu Guo Ling Yang Yiping Chen Kunquan Guo Kun Yang Handong Yang Yanfeng Zhou Yiwen Jiang Xiaomin Zhang Meian He Gang Liu Zhengming Chen Tangchun Wu Shouling Wu Liming Li An Pan Jing Ni |
| author_sort | Yanbo Zhang |
| collection | DOAJ |
| description | Abstract. Background:. Evidence on the relations of the American Heart Association's ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained unclear. We aimed to fill the gaps.
Methods:. A total of 198,164 participants without cancer and cardiovascular disease (CVD) were included from the China Kadoorie Biobank study (2004–2018), Dongfeng-Tongji cohort (2008–2018), and Kailuan study (2006–2019). Four behaviors (i.e., smoking, physical activity, diet, body mass index) and three medical factors (i.e., blood pressure, blood glucose, and blood lipid) were classified into poor, intermediate, and ideal levels (0, 1, and 2 points), which constituted 8-point behavioral, 6-point medical, and 14-point ICH scores. Results of Cox regression from three cohorts were pooled using random-effects models of meta-analysis.
Results:. During about 2 million person-years, 20,176 deaths were recorded. After controlling for demographic characteristics and alcohol drinking, hazard ratios (95% confidence intervals) comparing ICH scores of 10–14 vs. 0–6 were 0.52 (0.41–0.67), 0.44 (0.37–0.53), 0.54 (0.45–0.66), and 0.86 (0.64–1.14) for all-cause, CVD, respiratory, and cancer mortality. A higher behavioral or medical score was independently associated with lower all-cause and CVD mortality among the total population and populations with different levels of behavioral or medical health equally, and no interaction was observed.
Conclusions:. ICH was associated with lower all-cause, CVD, and respiratory mortality among Chinese adults. Both behavioral and medical health should be improved to prevent premature deaths. |
| first_indexed | 2024-04-09T16:10:43Z |
| format | Article |
| id | doaj.art-0c34377001bf4066b7acb20f2974e00c |
| institution | Directory Open Access Journal |
| issn | 0366-6999 2542-5641 |
| language | English |
| last_indexed | 2024-04-09T16:10:43Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj.art-0c34377001bf4066b7acb20f2974e00c2023-04-24T10:06:35ZengWolters KluwerChinese Medical Journal0366-69992542-56412023-01-01136214114910.1097/CM9.0000000000002379202301200-00003Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adultsYanbo ZhangCanqing YuShuohua ChenZhouzheng TuMengyi ZhengJun LvGuodong WangYan LiuJiaxin YuYu GuoLing YangYiping ChenKunquan GuoKun YangHandong YangYanfeng ZhouYiwen JiangXiaomin ZhangMeian HeGang LiuZhengming ChenTangchun WuShouling WuLiming LiAn PanJing NiAbstract. Background:. Evidence on the relations of the American Heart Association's ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained unclear. We aimed to fill the gaps. Methods:. A total of 198,164 participants without cancer and cardiovascular disease (CVD) were included from the China Kadoorie Biobank study (2004–2018), Dongfeng-Tongji cohort (2008–2018), and Kailuan study (2006–2019). Four behaviors (i.e., smoking, physical activity, diet, body mass index) and three medical factors (i.e., blood pressure, blood glucose, and blood lipid) were classified into poor, intermediate, and ideal levels (0, 1, and 2 points), which constituted 8-point behavioral, 6-point medical, and 14-point ICH scores. Results of Cox regression from three cohorts were pooled using random-effects models of meta-analysis. Results:. During about 2 million person-years, 20,176 deaths were recorded. After controlling for demographic characteristics and alcohol drinking, hazard ratios (95% confidence intervals) comparing ICH scores of 10–14 vs. 0–6 were 0.52 (0.41–0.67), 0.44 (0.37–0.53), 0.54 (0.45–0.66), and 0.86 (0.64–1.14) for all-cause, CVD, respiratory, and cancer mortality. A higher behavioral or medical score was independently associated with lower all-cause and CVD mortality among the total population and populations with different levels of behavioral or medical health equally, and no interaction was observed. Conclusions:. ICH was associated with lower all-cause, CVD, and respiratory mortality among Chinese adults. Both behavioral and medical health should be improved to prevent premature deaths.http://journals.lww.com/10.1097/CM9.0000000000002379 |
| spellingShingle | Yanbo Zhang Canqing Yu Shuohua Chen Zhouzheng Tu Mengyi Zheng Jun Lv Guodong Wang Yan Liu Jiaxin Yu Yu Guo Ling Yang Yiping Chen Kunquan Guo Kun Yang Handong Yang Yanfeng Zhou Yiwen Jiang Xiaomin Zhang Meian He Gang Liu Zhengming Chen Tangchun Wu Shouling Wu Liming Li An Pan Jing Ni Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults Chinese Medical Journal |
| title | Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults |
| title_full | Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults |
| title_fullStr | Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults |
| title_full_unstemmed | Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults |
| title_short | Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults |
| title_sort | ideal cardiovascular health and mortality pooled results of three prospective cohorts in chinese adults |
| url | http://journals.lww.com/10.1097/CM9.0000000000002379 |
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