The Decrease in Farnesoid X Receptor, Pregnane X Receptor and Constitutive Androstane Receptor in the Liver after Intestinal Ischemia-Reperfusion
Purpose. Intestinal ischemia-reperfusion (I/R) damages remote organs, including the liver, and promotes multi-organ failure (MOF). However, the molecular mechanisms underlying acute liver injury after intestinal I/R have not been completely elucidated. Farnesoid X receptor (FXR), pregnane X receptor...
Main Authors: | Jiro Ogura, Yusuke Terada, Takashi Tsujimoto, Takahiro Koizumi, Kaori Kuwayama, Hajime Maruyama, Asuka Fujikawa, Atsushi Takaya, Masaki Kobayashi, Shirou Itagaki, Natsuko Takahashi, Takeshi Hirano, Hiroaki Yamaguchi, Ken Iseki |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-11-01
|
Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/16649 |
Similar Items
-
Structural and functional similarity of amphibian constitutive androstane receptor with mammalian pregnane X receptor.
by: Marianne Mathäs, et al.
Published: (2014-01-01) -
Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
Published: (2014-01-01) -
Promoter DNA methylation of farnesoid X receptor and pregnane X receptor modulates the intrahepatic cholestasis of pregnancy phenotype.
by: Romina Cabrerizo, et al.
Published: (2014-01-01) -
Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation.
by: Marija Pinne, et al.
Published: (2016-01-01) -
Intestinal Ischemia-Reperfusion Increases Efflux for Uric Acid Via Paracellular Route in the Intestine, but Decreases that Via Transcellular Route Mediated by BCRP
by: Jiro Ogura, et al.
Published: (2012-04-01)