Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital

Abstract Background and Aim The aim of this study was to investigate the antibiotics used in patients with acute pancreatitis and evaluate their appropriateness. Methods We conducted a descriptive cross‐sectional study on 136 patients aged 18 years or older who were diagnosed with acute pancreatitis...

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Main Authors: Vo Duy Thong, Trinh Thi Hong Anh, Bui Thi Huong Quynh, Ngo Thi Thanh Quyt
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:JGH Open
Subjects:
Online Access:https://doi.org/10.1002/jgh3.12461
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author Vo Duy Thong
Trinh Thi Hong Anh
Bui Thi Huong Quynh
Ngo Thi Thanh Quyt
author_facet Vo Duy Thong
Trinh Thi Hong Anh
Bui Thi Huong Quynh
Ngo Thi Thanh Quyt
author_sort Vo Duy Thong
collection DOAJ
description Abstract Background and Aim The aim of this study was to investigate the antibiotics used in patients with acute pancreatitis and evaluate their appropriateness. Methods We conducted a descriptive cross‐sectional study on 136 patients aged 18 years or older who were diagnosed with acute pancreatitis and admitted to a national hospital in Ho Chi Minh City from January 2017 to December 2018. Medical records of patients were reviewed for data analysis, including epidemiological characteristics, pathological characteristics, treatment methods, and treatment effectiveness. Results There were 69.9% men and 30.1% women with a median age of 49.9 years. The most common etiologies included alcohol (21.3%), gallstones (23.6%), and hypertriglyceridemia (19.9%). The proportions of mild, moderate, and severe disease were 54.4, 39.0, and 6.6%, respectively. Antibiotics were given in 52.2% of patients. Although antibiotic prophylaxis was not recommended, 23.5% of cases used prophylactic antibiotics when there were no suspicion or evidence of infection. Conclusions Our study suggests that it is necessary to optimize the appropriateness of antibiotic indications for patients with acute pancreatitis.
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spelling doaj.art-0c3e8c69afe04132a78f8fe239294f192022-12-21T21:55:53ZengWileyJGH Open2397-90702021-01-015112813210.1002/jgh3.12461Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospitalVo Duy Thong0Trinh Thi Hong Anh1Bui Thi Huong Quynh2Ngo Thi Thanh Quyt3Department of Internal Medicine Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh city Ho Chi Minh City VietnamDepartment of Clinical Pharmacy Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh city Ho Chi Minh City VietnamDepartment of Clinical Pharmacy Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh city Ho Chi Minh City VietnamThong Nhat Hospital Ho Chi Minh City VietnamAbstract Background and Aim The aim of this study was to investigate the antibiotics used in patients with acute pancreatitis and evaluate their appropriateness. Methods We conducted a descriptive cross‐sectional study on 136 patients aged 18 years or older who were diagnosed with acute pancreatitis and admitted to a national hospital in Ho Chi Minh City from January 2017 to December 2018. Medical records of patients were reviewed for data analysis, including epidemiological characteristics, pathological characteristics, treatment methods, and treatment effectiveness. Results There were 69.9% men and 30.1% women with a median age of 49.9 years. The most common etiologies included alcohol (21.3%), gallstones (23.6%), and hypertriglyceridemia (19.9%). The proportions of mild, moderate, and severe disease were 54.4, 39.0, and 6.6%, respectively. Antibiotics were given in 52.2% of patients. Although antibiotic prophylaxis was not recommended, 23.5% of cases used prophylactic antibiotics when there were no suspicion or evidence of infection. Conclusions Our study suggests that it is necessary to optimize the appropriateness of antibiotic indications for patients with acute pancreatitis.https://doi.org/10.1002/jgh3.12461acute pancreatitisantibiotic usetreatment
spellingShingle Vo Duy Thong
Trinh Thi Hong Anh
Bui Thi Huong Quynh
Ngo Thi Thanh Quyt
Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
JGH Open
acute pancreatitis
antibiotic use
treatment
title Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
title_full Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
title_fullStr Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
title_full_unstemmed Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
title_short Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital
title_sort investigation of antibiotic use in patients with acute pancreatitis in a vietnamese hospital
topic acute pancreatitis
antibiotic use
treatment
url https://doi.org/10.1002/jgh3.12461
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