A Systematic Review on the Therapeutic Potentiality of PD-L1-Inhibiting MicroRNAs for Triple-Negative Breast Cancer: Toward Single-Cell Sequencing-Guided Biomimetic Delivery

A Systematic Review on the Therapeutic Potentiality of PD-L1-Inhibiting MicroRNAs for Triple-Negative Breast Cancer: Toward Single-Cell Sequencing-Guided Biomimetic Delivery

The programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) is a well-established inhibitory immune checkpoint axis in triple-negative breast cancer (TNBC). Growing evidence indicates that tumoral PD-L1 can lead to TNBC development. Although conventional immune checkpoint inhibitors...

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Bibliographic Details
Main Authors: Mahdi Abdoli Shadbad, Sahar Safaei, Oronzo Brunetti, Afshin Derakhshani, Parisa Lotfinejad, Ahad Mokhtarzadeh, Nima Hemmat, Vito Racanelli, Antonio Giovanni Solimando, Antonella Argentiero, Nicola Silvestris, Behzad Baradaran
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Genes
Subjects:
programmed death-ligand 1
PD-L1
triple-negative breast cancer
TNBC
microRNA
microRNA-based gene-therapy
Online Access:https://www.mdpi.com/2073-4425/12/8/1206

Internet

https://www.mdpi.com/2073-4425/12/8/1206

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