6-Chloro-3-nitro-2-[(phenylsulfonyl)methyl]imidazo[1,2-<i>b</i>]pyridazine

6-Chloro-3-nitro-2-[(phenylsulfonyl)methyl]imidazo[1,2-<i>b</i>]pyridazine

As part of our ongoing scaffold-hopping work on an antikinetoplastid 3-nitroimidazo[1,2-<i>a</i>]pyridine scaffold, we explored 3-nitroimidazo[1,2-<i>b</i>]pyridazine as a potential new antikinetoplastid series. Using conditions previously described by our lab, we obtained 6-...

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Bibliographic Details
Main Authors: Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molbank
Subjects:
imidazo[1,2-<i>b</i>]pyridazine
nitroaromatic
scaffold-hopping
structure-activity relationships
<i>Leishmania</i> spp.
<i>Trypanosoma brucei</i>
Online Access:https://www.mdpi.com/1422-8599/2023/1/M1573

Internet

https://www.mdpi.com/1422-8599/2023/1/M1573

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