Role of acetylation in doxorubicin-induced cardiotoxicity

Role of acetylation in doxorubicin-induced cardiotoxicity

As a potent chemotherapeutic agent, doxorubicin (DOX) is widely used for the treatment of a variety of cancers However, its clinical utility is limited by dose-dependent cardiotoxicity, and pathogenesis has traditionally been attributed to the formation of reactive oxygen species (ROS). Accordingly,...

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Bibliographic Details
Main Authors: Daisong Li, Yanyan Yang, Shizhong Wang, Xiangqin He, Meixin Liu, Baochen Bai, Chao Tian, Ruicong Sun, Tao Yu, Xianming Chu
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Redox Biology
Subjects:
Cardiotoxicity
Doxorubicin
Acetylation
Oxidative stress
Programmed cell death
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002482

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