Integration of genomic variants and bioinformatic-based approach to drive drug repurposing for multiple sclerosis

Integration of genomic variants and bioinformatic-based approach to drive drug repurposing for multiple sclerosis

Multiple sclerosis (MS) is a chronic autoimmune disease in the central nervous system (CNS) marked by inflammation, demyelination, and axonal loss. Currently available MS medication is limited, thereby calling for a strategy to accelerate new drug discovery. One of the strategies to discover new dru...

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Bibliographic Details
Main Authors: Arief Rahman Afief, Lalu Muhammad Irham, Wirawan Adikusuma, Dyah Aryani Perwitasari, Ageng Brahmadhi, Rocky Cheung
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Autoimmune disease
Bioinformatics
Drug repurposing
Genomic variants
Multiple sclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001376

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http://www.sciencedirect.com/science/article/pii/S2405580822001376

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