Conjugated surfactant micelles: A non‐denaturing purification platform for concentrated human immunoglobulin G

Conjugated surfactant micelles: A non‐denaturing purification platform for concentrated human immunoglobulin G

Abstract As downstream purification and separation technologies progress towards raising the concentration of therapeutic‐grade monoclonal antibodies (mAbs) in cell culture, downstream processing has begun to face increased difficulty in efficiently coping with such high immunoglobulin G (IgG) titer...

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Bibliographic Details
Main Authors: Gunasekaran Dhandapani, Ellen Wachtel, Guy Patchornik
Format: Article
Language:English
Published: Wiley-VCH 2023-06-01
Series:Nano Select
Subjects:
downstream processing
micellar conjugation
monoclonal antibodies
Protein A chromatography
purification
Online Access:https://doi.org/10.1002/nano.202200251

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