Dependence receptors: new targets for cancer therapy

Abstract Dependence receptors are known to promote survival and positive signaling such as proliferation, migration, and differentiation when activated, but to actively trigger apoptosis when unbound to their ligand. Their abnormal regulation was shown to be an important feature of tumorigenesis, al...

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Bibliographic Details
Main Authors: Morgan Brisset, Mélodie Grandin, Agnès Bernet, Patrick Mehlen, Frédéric Hollande
Format: Article
Language:English
Published: Springer Nature 2021-11-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.202114495