Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region
<b>Aims:</b> Extrapulmonary tuberculosis (EPTB) still constitutes an important clinical problem. We aimed to evaluate the incidence and features of extrapulmonary tuberculosis. <b> Materials and Methods:</b> We retrospectively evaluated 14,266 tuberculosis patients diagnose...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2007-01-01
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| Series: | Annals of Thoracic Medicine |
| Subjects: | |
| Online Access: | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2007;volume=2;issue=3;spage=118;epage=121;aulast=Ozvaran |
| _version_ | 1819268144985800704 |
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| author | Ozvaran Mustafa Baran Reha Tor Meltem Dilek Ilknur Demiryontar Dilay Arinc Sibel Toker Nil Chousein Efsun Sogukpinar Ozlem |
| author_facet | Ozvaran Mustafa Baran Reha Tor Meltem Dilek Ilknur Demiryontar Dilay Arinc Sibel Toker Nil Chousein Efsun Sogukpinar Ozlem |
| author_sort | Ozvaran Mustafa |
| collection | DOAJ |
| description | <b>Aims:</b> Extrapulmonary tuberculosis (EPTB) still constitutes an important clinical problem. We aimed to evaluate the incidence and features of extrapulmonary tuberculosis. <b> Materials and Methods:</b> We retrospectively evaluated 14,266 tuberculosis patients diagnosed between January 1999 and December 2003 in a tertiary care hospital in Istanbul. As many as 2,435 patients (17.1%) with EPTB were evaluated for the incidence and features. <b> Results:</b> Of the 14,266 patients, 4,154 were female (29%) and 10,112 were male (71%) and were aged between 14 and 86 years with a mean age of 35 ± 14 years. As many as 660 (17.9%) patients were diagnosed as EPTB in 1999, 568 (17.8%) in 2000, 357 (13.7%) in 2001, 462 (22%) in 2002 and 388 (14.5%) in 2003. EPTB presented most commonly as pleurisy (66%), followed by lymphadenitis (23%). Lymphadenitis and pleurisy were more commonly observed among female TB patients (60%) and among male TB patients (59%) respectively. EPTB showed a significant female predilection (26.8%) compared to male patients (13.1%). Multi-organ involvement was observed in 37 (1.5%) patients (two organs in 33 and three organs in 4). As many as 197 (8%) EPTB cases had pulmonary tuberculosis simultaneously. <b> Conclusions:</b> EPTB still constitutes an important clinical problem. The rates of EPTB have remained constant despite the decline in pulmonary tuberculosis cases. In the current study, we present our experience of the incidence and features of EPTB patients without HIV infection. In this study, EPTB cases constituted one-fifth of all tuberculosis cases presented to our center in the study period. |
| first_indexed | 2024-12-23T21:28:24Z |
| format | Article |
| id | doaj.art-0c50b5f51c7940ada6f984cba524b700 |
| institution | Directory Open Access Journal |
| issn | 1817-1737 |
| language | English |
| last_indexed | 2024-12-23T21:28:24Z |
| publishDate | 2007-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj.art-0c50b5f51c7940ada6f984cba524b7002022-12-21T17:30:31ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17372007-01-0123118121Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic regionOzvaran MustafaBaran RehaTor MeltemDilek IlknurDemiryontar DilayArinc SibelToker NilChousein EfsunSogukpinar Ozlem<b>Aims:</b> Extrapulmonary tuberculosis (EPTB) still constitutes an important clinical problem. We aimed to evaluate the incidence and features of extrapulmonary tuberculosis. <b> Materials and Methods:</b> We retrospectively evaluated 14,266 tuberculosis patients diagnosed between January 1999 and December 2003 in a tertiary care hospital in Istanbul. As many as 2,435 patients (17.1%) with EPTB were evaluated for the incidence and features. <b> Results:</b> Of the 14,266 patients, 4,154 were female (29%) and 10,112 were male (71%) and were aged between 14 and 86 years with a mean age of 35 ± 14 years. As many as 660 (17.9%) patients were diagnosed as EPTB in 1999, 568 (17.8%) in 2000, 357 (13.7%) in 2001, 462 (22%) in 2002 and 388 (14.5%) in 2003. EPTB presented most commonly as pleurisy (66%), followed by lymphadenitis (23%). Lymphadenitis and pleurisy were more commonly observed among female TB patients (60%) and among male TB patients (59%) respectively. EPTB showed a significant female predilection (26.8%) compared to male patients (13.1%). Multi-organ involvement was observed in 37 (1.5%) patients (two organs in 33 and three organs in 4). As many as 197 (8%) EPTB cases had pulmonary tuberculosis simultaneously. <b> Conclusions:</b> EPTB still constitutes an important clinical problem. The rates of EPTB have remained constant despite the decline in pulmonary tuberculosis cases. In the current study, we present our experience of the incidence and features of EPTB patients without HIV infection. In this study, EPTB cases constituted one-fifth of all tuberculosis cases presented to our center in the study period.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2007;volume=2;issue=3;spage=118;epage=121;aulast=OzvaranExtrapulmonary tuberculosisgenderincidencetuberculosis |
| spellingShingle | Ozvaran Mustafa Baran Reha Tor Meltem Dilek Ilknur Demiryontar Dilay Arinc Sibel Toker Nil Chousein Efsun Sogukpinar Ozlem Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region Annals of Thoracic Medicine Extrapulmonary tuberculosis gender incidence tuberculosis |
| title | Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region |
| title_full | Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region |
| title_fullStr | Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region |
| title_full_unstemmed | Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region |
| title_short | Extrapulmonary tuberculosis in non-human immunodeficiency virus-infected adults in an endemic region |
| title_sort | extrapulmonary tuberculosis in non human immunodeficiency virus infected adults in an endemic region |
| topic | Extrapulmonary tuberculosis gender incidence tuberculosis |
| url | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2007;volume=2;issue=3;spage=118;epage=121;aulast=Ozvaran |
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