Increased opioid dependence in a mouse model of panic disorder

Increased opioid dependence in a mouse model of panic disorder

Panic disorder is a highly prevalent neuropsychiatric disorder that shows co-occurrence with substance abuse. Here, we demonstrate that TrkC, the high affinity receptor for neurotrophin-3, is a key molecule involved in panic disorder and opiate dependence, using a transgenic mouse model (TgNTRK3). C...

Full description

Bibliographic Details
Main Authors: Xavier Gallego, Patricia Murtra, Teresa Zamalloa, Josep Maria Canals, Joseba Pineda, Alejandro Amador-Arjona, Rafael Maldonado, Mara Dierssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Locus Coeruleus
Panic Disorder
BDNF
TrkB
NT-3
opiate withdrawal
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.08.060.2009/full

Similar Items

Similar Items