Unexpected Role of Sterol Synthesis in RNA Stability and Translation in <i>Leishmania</i>

Unexpected Role of Sterol Synthesis in RNA Stability and Translation in <i>Leishmania</i>

<i>Leishmania</i> parasites are trypanosomatid protozoans that cause leishmaniasis affecting millions of people worldwide. Sterols are important components of the plasma and organellar membranes. They also serve as precursors for the synthesis of signaling molecules. Unlike animals, <...

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Bibliographic Details
Main Authors: Zemfira N. Karamysheva, Samrat Moitra, Andrea Perez, Sumit Mukherjee, Elena B. Tikhonova, Andrey L. Karamyshev, Kai Zhang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
<i>Leishmania</i>
sterol
C-14-demethylase
stress tolerance
RNA degradation
polysome
Online Access:https://www.mdpi.com/2227-9059/9/6/696

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