Is Pethidine Safe during Labor? Systematic Review

Abstract Purpose To verify if pethidine is safe for the conceptus when used during labor. Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases. Results A total of 17 studies published from January 1st, 2000, to...

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Main Authors: Rogevando Rodrigues Nunes, Paulo Giordano Baima Colares, Juliana Pinto Montenegro
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2017-12-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017001200686&tlng=en
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author Rogevando Rodrigues Nunes
Paulo Giordano Baima Colares
Juliana Pinto Montenegro
author_facet Rogevando Rodrigues Nunes
Paulo Giordano Baima Colares
Juliana Pinto Montenegro
author_sort Rogevando Rodrigues Nunes
collection DOAJ
description Abstract Purpose To verify if pethidine is safe for the conceptus when used during labor. Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases. Results A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. There was no record of conceptus vitality decrease associated with low doses of pethidine being administered to mothers during labor. Conclusions Intramuscular (IM) or intravenous (IV) pethidine at low doses, of up to 50 mg, is safe to administer during labor.
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spelling doaj.art-0c576143cd254ae2848afc57126d8c922022-12-22T04:15:57ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032017-12-01391268669110.1055/s-0037-1604065Is Pethidine Safe during Labor? Systematic ReviewRogevando Rodrigues NunesPaulo Giordano Baima ColaresJuliana Pinto MontenegroAbstract Purpose To verify if pethidine is safe for the conceptus when used during labor. Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases. Results A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. There was no record of conceptus vitality decrease associated with low doses of pethidine being administered to mothers during labor. Conclusions Intramuscular (IM) or intravenous (IV) pethidine at low doses, of up to 50 mg, is safe to administer during labor.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017001200686&tlng=enpethidinesafetylabor
spellingShingle Rogevando Rodrigues Nunes
Paulo Giordano Baima Colares
Juliana Pinto Montenegro
Is Pethidine Safe during Labor? Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia
pethidine
safety
labor
title Is Pethidine Safe during Labor? Systematic Review
title_full Is Pethidine Safe during Labor? Systematic Review
title_fullStr Is Pethidine Safe during Labor? Systematic Review
title_full_unstemmed Is Pethidine Safe during Labor? Systematic Review
title_short Is Pethidine Safe during Labor? Systematic Review
title_sort is pethidine safe during labor systematic review
topic pethidine
safety
labor
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017001200686&tlng=en
work_keys_str_mv AT rogevandorodriguesnunes ispethidinesafeduringlaborsystematicreview
AT paulogiordanobaimacolares ispethidinesafeduringlaborsystematicreview
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