Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice

Abstract Previous work has shown that motor skill learning stimulates and requires generation of myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult mice. In the present study we ask whether OL production is also required for non-motor learning and cognition,...

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Bibliographic Details
Main Authors: Takahiro Shimizu, Stuart G. Nayar, Matthew Swire, Yi Jiang, Matthew Grist, Malte Kaller, Cassandra Sampaio Baptista, David M. Bannerman, Heidi Johansen-Berg, Katsutoshi Ogasawara, Koujiro Tohyama, Huiliang Li, William D. Richardson
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42293-4