External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers
Diabetic foot ulcers are one of the most severe complications of diabetes that have imposed great financial and psychological burdens on diabetic patients. A Nocardia rubra cell wall skeleton (Nr-CWS) can be externally applied to accelerate wound healing. However, its clinical application has not ye...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co. Ltd.
2022-03-01
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| Series: | Chinese Journal of Plastic and Reconstructive Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2096691122000036 |
| _version_ | 1828090098962399232 |
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| author | Caiqi Shen Wuhan Wei Aijun Zhang Changbo Tao Xueyang Li Yanping Guo Hanxiao Wei Qiang Li Peisheng Jin |
| author_facet | Caiqi Shen Wuhan Wei Aijun Zhang Changbo Tao Xueyang Li Yanping Guo Hanxiao Wei Qiang Li Peisheng Jin |
| author_sort | Caiqi Shen |
| collection | DOAJ |
| description | Diabetic foot ulcers are one of the most severe complications of diabetes that have imposed great financial and psychological burdens on diabetic patients. A Nocardia rubra cell wall skeleton (Nr-CWS) can be externally applied to accelerate wound healing. However, its clinical application has not yet been reported. Herein, we report two patients with diabetic foot ulcers treated with Nr-CWS. After wound debridement, the wound was covered with a sterile cotton ball infiltrated with an Nr-CWS that was diluted with 2.0 mL of saline. The covers were changed every two days until complete wound healing occurred. The two wounds healed after 3 and 12 weeks, respectively. This article aims to provide a new treatment for diabetic foot ulcers, with the hope that physicians may consider an Nr-CWS as a complementary method for the treatment of chronic wounds. |
| first_indexed | 2024-04-11T05:51:45Z |
| format | Article |
| id | doaj.art-0c5a49b3b3e84a55bbcdc86f8f285250 |
| institution | Directory Open Access Journal |
| issn | 2096-6911 |
| language | English |
| last_indexed | 2024-04-11T05:51:45Z |
| publishDate | 2022-03-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Chinese Journal of Plastic and Reconstructive Surgery |
| spelling | doaj.art-0c5a49b3b3e84a55bbcdc86f8f2852502022-12-22T04:42:03ZengKeAi Communications Co. Ltd.Chinese Journal of Plastic and Reconstructive Surgery2096-69112022-03-01411719External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcersCaiqi Shen0Wuhan Wei1Aijun Zhang2Changbo Tao3Xueyang Li4Yanping Guo5Hanxiao Wei6Qiang Li7Peisheng Jin8Department of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaGraduate School, Xuzhou Medical University, Xuzhou 221004, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, ChinaDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, China; Corresponding authors. Department of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Huaihai West Road, Xuzhou 221002, Jiangsu, China.Department of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, China; Corresponding authors. Department of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Huaihai West Road, Xuzhou 221002, Jiangsu, China.Diabetic foot ulcers are one of the most severe complications of diabetes that have imposed great financial and psychological burdens on diabetic patients. A Nocardia rubra cell wall skeleton (Nr-CWS) can be externally applied to accelerate wound healing. However, its clinical application has not yet been reported. Herein, we report two patients with diabetic foot ulcers treated with Nr-CWS. After wound debridement, the wound was covered with a sterile cotton ball infiltrated with an Nr-CWS that was diluted with 2.0 mL of saline. The covers were changed every two days until complete wound healing occurred. The two wounds healed after 3 and 12 weeks, respectively. This article aims to provide a new treatment for diabetic foot ulcers, with the hope that physicians may consider an Nr-CWS as a complementary method for the treatment of chronic wounds.http://www.sciencedirect.com/science/article/pii/S2096691122000036Diabetic foot ulcerNocardia rubra cell wall skeletonExternal applicationWound healing |
| spellingShingle | Caiqi Shen Wuhan Wei Aijun Zhang Changbo Tao Xueyang Li Yanping Guo Hanxiao Wei Qiang Li Peisheng Jin External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers Chinese Journal of Plastic and Reconstructive Surgery Diabetic foot ulcer Nocardia rubra cell wall skeleton External application Wound healing |
| title | External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| title_full | External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| title_fullStr | External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| title_full_unstemmed | External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| title_short | External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| title_sort | external application of a nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers |
| topic | Diabetic foot ulcer Nocardia rubra cell wall skeleton External application Wound healing |
| url | http://www.sciencedirect.com/science/article/pii/S2096691122000036 |
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