Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy
The aim of this study is to investigate the feasibility of manufacturing thin real-time relative dosimeters for clinical radiotherapy (RT) with potential applications for transmission monitoring in vivo dosimetry and pre-treatment dose verifications. Thin (≈1 μm) layers of a high sensitivity, wide b...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-11-01
|
| Series: | Zeitschrift für Medizinische Physik |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0939388922000265 |
| _version_ | 1797385262642233344 |
|---|---|
| author | Mara Bruzzi Nicola Calisi Matteo Latino Naomi Falsini Anna Vinattieri Cinzia Talamonti |
| author_facet | Mara Bruzzi Nicola Calisi Matteo Latino Naomi Falsini Anna Vinattieri Cinzia Talamonti |
| author_sort | Mara Bruzzi |
| collection | DOAJ |
| description | The aim of this study is to investigate the feasibility of manufacturing thin real-time relative dosimeters for clinical radiotherapy (RT) with potential applications for transmission monitoring in vivo dosimetry and pre-treatment dose verifications. Thin (≈1 μm) layers of a high sensitivity, wide bandgap semiconductor, the inorganic perovskite CsPbCl3, have been grown for the first time by magnetron sputtering on plastic substrates equipped with electrode arrays. Prototype devices have been tested in real-time configuration to evaluate the dose delivered by a 6 MV photon beam from a linear accelerator. Linearity of the charge with the dose has been verified over three order of magnitudes, linearity of the current signal with the dose rate has been also successfully tested in the range 0.5-4.3 Gy/min. The combination of high sensitivity per unit volume and wide bandgap provides high signal-to-noise ratios, up to 70, even at moderate applied voltages. The Schottky diode configuration allows the detector to operate without bias voltage (null bias).The blocking-barrier structure allows to confine the active volume within sub-millimetric sizes, a quite attractive feature in view to increase granularity and achieve the high spatial resolutions required in modern RT techniques. All the above-mentioned features indeed pave the way to a novel generation of flexible, transmission, real time dosimeters for clinical radiotherapy. |
| first_indexed | 2024-03-08T21:51:42Z |
| format | Article |
| id | doaj.art-0c5d32c1fdea4b709bbf5a69a7ea6a57 |
| institution | Directory Open Access Journal |
| issn | 0939-3889 |
| language | English |
| last_indexed | 2024-03-08T21:51:42Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Zeitschrift für Medizinische Physik |
| spelling | doaj.art-0c5d32c1fdea4b709bbf5a69a7ea6a572023-12-20T07:33:16ZengElsevierZeitschrift für Medizinische Physik0939-38892022-11-01324392402Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical RadiotherapyMara Bruzzi0Nicola Calisi1Matteo Latino2Naomi Falsini3Anna Vinattieri4Cinzia Talamonti5Dipartimento di Fisica e Astronomia, Università degli Studi di Firenze, Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy; I.N.F.N. Sezione di Firenze Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy; Corresponding author: Mara Bruzzi, Dipartimento di Fisica e Astronomia, Università degli Studi di Firenze, Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy / N.F.N. Sezione di Firenze Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy.Dipartimento di Ingegneria Industriale, Università degli Studi di Firenze, Via S. Marta 3, 50139, Firenze, ItalyDipartimento di Scienze dell’Informazione, Università degli Studi di Firenze, Via S. Marta 3, 50139, Firenze, ItalyDipartimento di Fisica e Astronomia, Università degli Studi di Firenze, Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy; ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Fusion and Technology for Nuclear Safety and Security Department, Nuclear Safety, Security and Sustainability Division, via Martiri di Monte Sole 4, 40129, Bologna, ItalyDipartimento di Fisica e Astronomia, Università degli Studi di Firenze, Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy; I.N.F.N. Sezione di Firenze Via G. Sansone 1, 50019, Sesto Fiorentino, FI, ItalyI.N.F.N. Sezione di Firenze Via G. Sansone 1, 50019, Sesto Fiorentino, FI, Italy; Dipartimento di Scienze Biomediche Sperimentali e Cliniche “Mario Serio”, Università degli Studi di Firenze, Firenze, ItalyThe aim of this study is to investigate the feasibility of manufacturing thin real-time relative dosimeters for clinical radiotherapy (RT) with potential applications for transmission monitoring in vivo dosimetry and pre-treatment dose verifications. Thin (≈1 μm) layers of a high sensitivity, wide bandgap semiconductor, the inorganic perovskite CsPbCl3, have been grown for the first time by magnetron sputtering on plastic substrates equipped with electrode arrays. Prototype devices have been tested in real-time configuration to evaluate the dose delivered by a 6 MV photon beam from a linear accelerator. Linearity of the charge with the dose has been verified over three order of magnitudes, linearity of the current signal with the dose rate has been also successfully tested in the range 0.5-4.3 Gy/min. The combination of high sensitivity per unit volume and wide bandgap provides high signal-to-noise ratios, up to 70, even at moderate applied voltages. The Schottky diode configuration allows the detector to operate without bias voltage (null bias).The blocking-barrier structure allows to confine the active volume within sub-millimetric sizes, a quite attractive feature in view to increase granularity and achieve the high spatial resolutions required in modern RT techniques. All the above-mentioned features indeed pave the way to a novel generation of flexible, transmission, real time dosimeters for clinical radiotherapy.http://www.sciencedirect.com/science/article/pii/S0939388922000265Radiation detectorsDosimetersRadiotherapyMetal halide perovskiteThin films |
| spellingShingle | Mara Bruzzi Nicola Calisi Matteo Latino Naomi Falsini Anna Vinattieri Cinzia Talamonti Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy Zeitschrift für Medizinische Physik Radiation detectors Dosimeters Radiotherapy Metal halide perovskite Thin films |
| title | Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy |
| title_full | Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy |
| title_fullStr | Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy |
| title_full_unstemmed | Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy |
| title_short | Magnetron Sputtered CsPbCl3 Perovskite Detectors as Real-Time Dosimeters for Clinical Radiotherapy |
| title_sort | magnetron sputtered cspbcl3 perovskite detectors as real time dosimeters for clinical radiotherapy |
| topic | Radiation detectors Dosimeters Radiotherapy Metal halide perovskite Thin films |
| url | http://www.sciencedirect.com/science/article/pii/S0939388922000265 |
| work_keys_str_mv | AT marabruzzi magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy AT nicolacalisi magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy AT matteolatino magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy AT naomifalsini magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy AT annavinattieri magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy AT cinziatalamonti magnetronsputteredcspbcl3perovskitedetectorsasrealtimedosimetersforclinicalradiotherapy |