Glucosamine-Modified Reduction-Responsive Polymeric Micelles for Liver Cancer Therapy

Glucosamine-Modified Reduction-Responsive Polymeric Micelles for Liver Cancer Therapy

In this work, glucose transporter-1 (GLUT-1) and glutathione (GSH) over-expression in liver cancer was utilized to design a reduction-responsive and active targeting drug delivery system AG-PEG-SS-PCL (APSP) for the delivery of sorafenib (SF). The SF-APSP micelles were prepared using the thin film h...

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Bibliographic Details
Main Authors: Lei Meng, Fangshu Liu, Chenchen Du, Jiaying Zhu, Qian Xiong, Jing Li, Weitong Sun
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
liver cancer
glucosamine
sorafenib
reduction-responsive
polymer micelles
Online Access:https://www.mdpi.com/1420-3049/28/9/3824

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