Association of sarcopenia with important health conditions among community-dwelling Asian women
This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and functio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/?tool=EBI |
| _version_ | 1811173515077877760 |
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| author | Beverly Wen-Xin Wong Win Pa Pa Thu Yiong Huak Chan Susan Jane Sinclair Logan Jane A. Cauley Eu-Leong Yong |
| author_facet | Beverly Wen-Xin Wong Win Pa Pa Thu Yiong Huak Chan Susan Jane Sinclair Logan Jane A. Cauley Eu-Leong Yong |
| author_sort | Beverly Wen-Xin Wong |
| collection | DOAJ |
| description | This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria. |
| first_indexed | 2024-04-10T17:48:15Z |
| format | Article |
| id | doaj.art-0c61f06fbbc04e1284500da11f00cf7e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T17:48:15Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-0c61f06fbbc04e1284500da11f00cf7e2023-02-02T22:58:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01181Association of sarcopenia with important health conditions among community-dwelling Asian womenBeverly Wen-Xin WongWin Pa Pa ThuYiong Huak ChanSusan Jane Sinclair LoganJane A. CauleyEu-Leong YongThis study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/?tool=EBI |
| spellingShingle | Beverly Wen-Xin Wong Win Pa Pa Thu Yiong Huak Chan Susan Jane Sinclair Logan Jane A. Cauley Eu-Leong Yong Association of sarcopenia with important health conditions among community-dwelling Asian women PLoS ONE |
| title | Association of sarcopenia with important health conditions among community-dwelling Asian women |
| title_full | Association of sarcopenia with important health conditions among community-dwelling Asian women |
| title_fullStr | Association of sarcopenia with important health conditions among community-dwelling Asian women |
| title_full_unstemmed | Association of sarcopenia with important health conditions among community-dwelling Asian women |
| title_short | Association of sarcopenia with important health conditions among community-dwelling Asian women |
| title_sort | association of sarcopenia with important health conditions among community dwelling asian women |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/?tool=EBI |
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