Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore
The discovery of Toxoplasma gondii independently by Nicolle and Manceaux (1908) and Splendore (1908) was to open a "Pandora's Box" that has led research on this parasite into a number of scientific disciplines. In the 100 years since its discovery, the mystery surrounding T. gondii an...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2009-03-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000200003 |
| _version_ | 1827879675076018176 |
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| author | David J P Ferguson |
| author_facet | David J P Ferguson |
| author_sort | David J P Ferguson |
| collection | DOAJ |
| description | The discovery of Toxoplasma gondii independently by Nicolle and Manceaux (1908) and Splendore (1908) was to open a "Pandora's Box" that has led research on this parasite into a number of scientific disciplines. In the 100 years since its discovery, the mystery surrounding T. gondii and its inter-relationship with humans has continued to provide a stimulating source of material in many areas of research, resulting in the publication of almost 20,000 papers and a number of books. This flood of diverse information shows no sign of abating, with an average of 10 papers per week appearing in PubMed. Herein, it is impossible to do more than provide a very superficial comment on what has become a massive body of scientific information. T. gondii has many unique features and seems to be the "exception to almost every rule" thus acting as a focus for research in disciplines from epidemiology to immunology to human behaviour to cell biology to human disease. In this review a number of the historical advances will be mentioned and combined with a description of the basic biology of the parasite. |
| first_indexed | 2024-03-12T18:09:58Z |
| format | Article |
| id | doaj.art-0c62fbb1d2744e8c8f717eb3a7d2b1f5 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:09:58Z |
| publishDate | 2009-03-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-0c62fbb1d2744e8c8f717eb3a7d2b1f52023-08-02T09:15:54ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602009-03-01104213314810.1590/S0074-02762009000200003Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and SplendoreDavid J P FergusonThe discovery of Toxoplasma gondii independently by Nicolle and Manceaux (1908) and Splendore (1908) was to open a "Pandora's Box" that has led research on this parasite into a number of scientific disciplines. In the 100 years since its discovery, the mystery surrounding T. gondii and its inter-relationship with humans has continued to provide a stimulating source of material in many areas of research, resulting in the publication of almost 20,000 papers and a number of books. This flood of diverse information shows no sign of abating, with an average of 10 papers per week appearing in PubMed. Herein, it is impossible to do more than provide a very superficial comment on what has become a massive body of scientific information. T. gondii has many unique features and seems to be the "exception to almost every rule" thus acting as a focus for research in disciplines from epidemiology to immunology to human behaviour to cell biology to human disease. In this review a number of the historical advances will be mentioned and combined with a description of the basic biology of the parasite.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000200003Toxoplasma gondiitoxoplasmosishistorylife cycledevelopmental stages |
| spellingShingle | David J P Ferguson Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore Memorias do Instituto Oswaldo Cruz Toxoplasma gondii toxoplasmosis history life cycle developmental stages |
| title | Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore |
| title_full | Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore |
| title_fullStr | Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore |
| title_full_unstemmed | Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore |
| title_short | Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore |
| title_sort | toxoplasma gondii 1908 2008 homage to nicolle manceaux and splendore |
| topic | Toxoplasma gondii toxoplasmosis history life cycle developmental stages |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000200003 |
| work_keys_str_mv | AT davidjpferguson toxoplasmagondii19082008homagetonicollemanceauxandsplendore |