Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases
Introduction. At the present moment, the healthcare system has faced significant problems in terms of infectious safety: an unprecedented increase in the spectrum of pathogenic microorganisms, the annual appearance of 1-2 “new” infectious diseases, an increase in the proportion of emergent infection...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2020-05-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/5621 |
| _version_ | 1797841606761512960 |
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| author | S. V. Ryazantsev S. V. Pavlova |
| author_facet | S. V. Ryazantsev S. V. Pavlova |
| author_sort | S. V. Ryazantsev |
| collection | DOAJ |
| description | Introduction. At the present moment, the healthcare system has faced significant problems in terms of infectious safety: an unprecedented increase in the spectrum of pathogenic microorganisms, the annual appearance of 1-2 “new” infectious diseases, an increase in the proportion of emergent infections, especially of viral etiology, against which there are no effective drugs, and the spread drug-resistant microorganisms, as well as the establishment of a direct etiological or trigger role of microbial agents in the development of somatic human pathology.The aim of our work was to evaluate the topical preparation (amylmetacresol and dichlorobenzyl alcohol) used to stop the inflammatory process and eliminate pain in patients with pharyngeal diseases.Patients and methods. We studied the antimicrobial, antiviral and anti-inflammatory effect of a fixed combination of 2,4-dichlorobenzyl alcohol 1.2 mg, amylmethacresol 0.6 mg. 20 patients with manifestations of inflammatory changes in the pharyngeal cavity underwent treatment with Strepsils resorption tablets according to the scheme. The control group consisted of 10 patients who received therapy according to the usual scheme.Results and discussion. As a result of the therapy, sore throat in patients in the first group completely disappeared amongst 15 patients, and its intensity significantly decreased amongst 5 patients. Patients noted that the use of Strepsils resorption tablets reduces the sensation of a foreign body, irritation in the pharynx and oral cavity; eliminates pain, tickle, feeling of soreness in the throat. The analgesic effect of the drug manifested itself after about 5 minutes and lasted up to 2 hours. By the end of the treatment, all patients from this group had unpleasant sensations and discomfort completely stopped.Conclusion. Amylmethacresol/Dichlorobenzyl Absorption Tablets is a well-tolerated and effective over-the-counter treatment offering functional, sensory and emotional benefits for patients with acute sore throat, providing a quick onset of effect and may be more relevant and suitable than antibiotics when pharyngitis associated with viral infections of the upper respiratory tract. |
| first_indexed | 2024-04-09T16:34:01Z |
| format | Article |
| id | doaj.art-0c6648c9642a4db29f0c96a715b2ff45 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:34:01Z |
| publishDate | 2020-05-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-0c6648c9642a4db29f0c96a715b2ff452023-04-23T06:56:57ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902020-05-0106142010.21518/2079-701X-2020-6-14-205111Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseasesS. V. Ryazantsev0S. V. Pavlova1Saint Petersburg Research Institute of Ear, Throat, Nose and SpeechSaint Petersburg Research Institute of Ear, Throat, Nose and SpeechIntroduction. At the present moment, the healthcare system has faced significant problems in terms of infectious safety: an unprecedented increase in the spectrum of pathogenic microorganisms, the annual appearance of 1-2 “new” infectious diseases, an increase in the proportion of emergent infections, especially of viral etiology, against which there are no effective drugs, and the spread drug-resistant microorganisms, as well as the establishment of a direct etiological or trigger role of microbial agents in the development of somatic human pathology.The aim of our work was to evaluate the topical preparation (amylmetacresol and dichlorobenzyl alcohol) used to stop the inflammatory process and eliminate pain in patients with pharyngeal diseases.Patients and methods. We studied the antimicrobial, antiviral and anti-inflammatory effect of a fixed combination of 2,4-dichlorobenzyl alcohol 1.2 mg, amylmethacresol 0.6 mg. 20 patients with manifestations of inflammatory changes in the pharyngeal cavity underwent treatment with Strepsils resorption tablets according to the scheme. The control group consisted of 10 patients who received therapy according to the usual scheme.Results and discussion. As a result of the therapy, sore throat in patients in the first group completely disappeared amongst 15 patients, and its intensity significantly decreased amongst 5 patients. Patients noted that the use of Strepsils resorption tablets reduces the sensation of a foreign body, irritation in the pharynx and oral cavity; eliminates pain, tickle, feeling of soreness in the throat. The analgesic effect of the drug manifested itself after about 5 minutes and lasted up to 2 hours. By the end of the treatment, all patients from this group had unpleasant sensations and discomfort completely stopped.Conclusion. Amylmethacresol/Dichlorobenzyl Absorption Tablets is a well-tolerated and effective over-the-counter treatment offering functional, sensory and emotional benefits for patients with acute sore throat, providing a quick onset of effect and may be more relevant and suitable than antibiotics when pharyngitis associated with viral infections of the upper respiratory tract.https://www.med-sovet.pro/jour/article/view/5621infectious inflammatory diseases of the pharynxsore throatthroat microbiometreatmenttopical therapymedications with complex actionamylmetacresoldichlorbenzylalkoholflurbiprophenum |
| spellingShingle | S. V. Ryazantsev S. V. Pavlova Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases Медицинский совет infectious inflammatory diseases of the pharynx sore throat throat microbiome treatment topical therapy medications with complex action amylmetacresol dichlorbenzylalkohol flurbiprophenum |
| title | Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| title_full | Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| title_fullStr | Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| title_full_unstemmed | Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| title_short | Modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| title_sort | modern possibilities of topical therapy of upper respiratory tract and throat infectious inflammatory diseases |
| topic | infectious inflammatory diseases of the pharynx sore throat throat microbiome treatment topical therapy medications with complex action amylmetacresol dichlorbenzylalkohol flurbiprophenum |
| url | https://www.med-sovet.pro/jour/article/view/5621 |
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