An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.

An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.

Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library in T. brucei bloodstream forms, we identified a member of the mitochondrial carrier family, TbMCP14,...

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Bibliographic Details
Main Authors: Juan P de Macêdo, Gabriela Schumann Burkard, Moritz Niemann, Michael P Barrett, Henri Vial, Pascal Mäser, Isabel Roditi, André Schneider, Peter Bütikofer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4422618?pdf=render

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