Induction of Apoptosis by Hypertension Via Endoplasmic Reticulum Stress

Induction of Apoptosis by Hypertension Via Endoplasmic Reticulum Stress

Background/Aims: Endoplasmic reticulum (ER) stress is one of the intrinsic apoptosis pathways, and cardiac apoptosis can occur in cardiovascular diseases, such as hypertension. However, the mechanisms by which ER stress leads to apoptosis remain enigmatic, particularly in the progression from cardia...

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Bibliographic Details
Main Authors: Yingying Sun, Tong Zhang, Li Li, Ji Wang
Format: Article
Language:English
Published: Karger Publishers 2015-02-01
Series:Kidney & Blood Pressure Research
Subjects:
Apoptosis
Caspase-12
CHOP
ER stress
GRP78
Hypertension
Online Access:http://www.karger.com/Article/FullText/368481

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