2136 Frequently overlooked challenges of pragmatic trials
OBJECTIVES/SPECIFIC AIMS: To review the multiple differences between traditional research design and on the ground pragmatic trials. To review two pragmatic projects, identify core assumptions and to contrast assumptions with the reality of conducting T3 and T4 research. METHODS/STUDY POPULATION: Ob...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2018-06-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866118002133/type/journal_article |
| _version_ | 1811156682928029696 |
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| author | Rodger S. Kessler |
| author_facet | Rodger S. Kessler |
| author_sort | Rodger S. Kessler |
| collection | DOAJ |
| description | OBJECTIVES/SPECIFIC AIMS: To review the multiple differences between traditional research design and on the ground pragmatic trials. To review two pragmatic projects, identify core assumptions and to contrast assumptions with the reality of conducting T3 and T4 research. METHODS/STUDY POPULATION: Observational mixed methods multi trial review of large multi site implementations. RESULTS/ANTICIPATED RESULTS: The complexities of implementation on the ground were consistently greater than anticipated and required changing assumptions and research design elements. DISCUSSION/SIGNIFICANCE OF IMPACT: Research findings are tremendously influenced by design and design implementation decisions. Anticipating the scope and breadth of the challenges will assist potential of successful implementation. |
| first_indexed | 2024-04-10T04:55:29Z |
| format | Article |
| id | doaj.art-0c6ffe19d7834432bf8e96ca73bcc7b0 |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-04-10T04:55:29Z |
| publishDate | 2018-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-0c6ffe19d7834432bf8e96ca73bcc7b02023-03-09T12:30:17ZengCambridge University PressJournal of Clinical and Translational Science2059-86612018-06-012565710.1017/cts.2018.2132136 Frequently overlooked challenges of pragmatic trialsRodger S. Kessler0Arizona State UniversityOBJECTIVES/SPECIFIC AIMS: To review the multiple differences between traditional research design and on the ground pragmatic trials. To review two pragmatic projects, identify core assumptions and to contrast assumptions with the reality of conducting T3 and T4 research. METHODS/STUDY POPULATION: Observational mixed methods multi trial review of large multi site implementations. RESULTS/ANTICIPATED RESULTS: The complexities of implementation on the ground were consistently greater than anticipated and required changing assumptions and research design elements. DISCUSSION/SIGNIFICANCE OF IMPACT: Research findings are tremendously influenced by design and design implementation decisions. Anticipating the scope and breadth of the challenges will assist potential of successful implementation.https://www.cambridge.org/core/product/identifier/S2059866118002133/type/journal_article |
| spellingShingle | Rodger S. Kessler 2136 Frequently overlooked challenges of pragmatic trials Journal of Clinical and Translational Science |
| title | 2136 Frequently overlooked challenges of pragmatic trials |
| title_full | 2136 Frequently overlooked challenges of pragmatic trials |
| title_fullStr | 2136 Frequently overlooked challenges of pragmatic trials |
| title_full_unstemmed | 2136 Frequently overlooked challenges of pragmatic trials |
| title_short | 2136 Frequently overlooked challenges of pragmatic trials |
| title_sort | 2136 frequently overlooked challenges of pragmatic trials |
| url | https://www.cambridge.org/core/product/identifier/S2059866118002133/type/journal_article |
| work_keys_str_mv | AT rodgerskessler 2136frequentlyoverlookedchallengesofpragmatictrials |