The factors affecting effectiveness of treatment in phages therapy, mini review

In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture....

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Main Author: Mai Huong eCHATAIN-LY
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/full
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author Mai Huong eCHATAIN-LY
author_facet Mai Huong eCHATAIN-LY
author_sort Mai Huong eCHATAIN-LY
collection DOAJ
description In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature ...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applications
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spelling doaj.art-0c73fa92d71c49ca96be41878f8286d42022-12-22T01:14:45ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2014-02-01510.3389/fmicb.2014.0005174029The factors affecting effectiveness of treatment in phages therapy, mini reviewMai Huong eCHATAIN-LY0ISARA-LYONIn recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature ...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applicationshttp://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/fulleffectivenessantibiotic resistancePhagephage therapypathogenic bacteria
spellingShingle Mai Huong eCHATAIN-LY
The factors affecting effectiveness of treatment in phages therapy, mini review
Frontiers in Microbiology
effectiveness
antibiotic resistance
Phage
phage therapy
pathogenic bacteria
title The factors affecting effectiveness of treatment in phages therapy, mini review
title_full The factors affecting effectiveness of treatment in phages therapy, mini review
title_fullStr The factors affecting effectiveness of treatment in phages therapy, mini review
title_full_unstemmed The factors affecting effectiveness of treatment in phages therapy, mini review
title_short The factors affecting effectiveness of treatment in phages therapy, mini review
title_sort factors affecting effectiveness of treatment in phages therapy mini review
topic effectiveness
antibiotic resistance
Phage
phage therapy
pathogenic bacteria
url http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/full
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