The factors affecting effectiveness of treatment in phages therapy, mini review
In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture....
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-02-01
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Series: | Frontiers in Microbiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/full |
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author | Mai Huong eCHATAIN-LY |
author_facet | Mai Huong eCHATAIN-LY |
author_sort | Mai Huong eCHATAIN-LY |
collection | DOAJ |
description | In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature ...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applications |
first_indexed | 2024-12-11T08:16:54Z |
format | Article |
id | doaj.art-0c73fa92d71c49ca96be41878f8286d4 |
institution | Directory Open Access Journal |
issn | 1664-302X |
language | English |
last_indexed | 2024-12-11T08:16:54Z |
publishDate | 2014-02-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Microbiology |
spelling | doaj.art-0c73fa92d71c49ca96be41878f8286d42022-12-22T01:14:45ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2014-02-01510.3389/fmicb.2014.0005174029The factors affecting effectiveness of treatment in phages therapy, mini reviewMai Huong eCHATAIN-LY0ISARA-LYONIn recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature ...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applicationshttp://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/fulleffectivenessantibiotic resistancePhagephage therapypathogenic bacteria |
spellingShingle | Mai Huong eCHATAIN-LY The factors affecting effectiveness of treatment in phages therapy, mini review Frontiers in Microbiology effectiveness antibiotic resistance Phage phage therapy pathogenic bacteria |
title | The factors affecting effectiveness of treatment in phages therapy, mini review |
title_full | The factors affecting effectiveness of treatment in phages therapy, mini review |
title_fullStr | The factors affecting effectiveness of treatment in phages therapy, mini review |
title_full_unstemmed | The factors affecting effectiveness of treatment in phages therapy, mini review |
title_short | The factors affecting effectiveness of treatment in phages therapy, mini review |
title_sort | factors affecting effectiveness of treatment in phages therapy mini review |
topic | effectiveness antibiotic resistance Phage phage therapy pathogenic bacteria |
url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00051/full |
work_keys_str_mv | AT maihuongechatainly thefactorsaffectingeffectivenessoftreatmentinphagestherapyminireview AT maihuongechatainly factorsaffectingeffectivenessoftreatmentinphagestherapyminireview |