Whole Aspect of Runx2 Functions in Skeletal Development

Whole Aspect of Runx2 Functions in Skeletal Development

Runt-related transcription factor 2 (Runx2) is a fundamental transcription factor for bone development. In endochondral ossification, Runx2 induces chondrocyte maturation, enhances chondrocyte proliferation through Indian hedgehog (Ihh) induction, and induces the expression of vascular endothelial g...

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Bibliographic Details
Main Author: Toshihisa Komori
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Runx2
chondrocyte differentiation
osteoblast proliferation
osteoblast differentiation
transdifferentiation
bone matrix proteins
Online Access:https://www.mdpi.com/1422-0067/23/10/5776

Internet

https://www.mdpi.com/1422-0067/23/10/5776

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