Whole Aspect of Runx2 Functions in Skeletal Development

Whole Aspect of Runx2 Functions in Skeletal Development

Runt-related transcription factor 2 (Runx2) is a fundamental transcription factor for bone development. In endochondral ossification, Runx2 induces chondrocyte maturation, enhances chondrocyte proliferation through Indian hedgehog (Ihh) induction, and induces the expression of vascular endothelial g...

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Bibliographic Details
Main Author:	Toshihisa Komori
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Series:	International Journal of Molecular Sciences
Subjects:	Runx2 chondrocyte differentiation osteoblast proliferation osteoblast differentiation transdifferentiation bone matrix proteins
Online Access:	https://www.mdpi.com/1422-0067/23/10/5776

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