Hierarchic regulation of a metabolic pathway: H-NS, CRP, and SsrB control myo-inositol utilization by Salmonella enterica

Hierarchic regulation of a metabolic pathway: H-NS, CRP, and SsrB control myo-inositol utilization by Salmonella enterica

ABSTRACT The metabolic island GEI4417/4436 of Salmonella enterica serovar Typhimurium (S. Typhimurium) enables the degradation of myo-inositol (MI) as the sole carbon and energy source. The island encodes two regulatory factors, the autoregulated repressor IolR that inhibits the transcription of mos...

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Bibliographic Details
Main Authors: Angela Felsl, Dominik Brokatzky, Carsten Kröger, Ralf Heermann, Thilo M. Fuchs
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
myo-inositol
H-NS
CRP
SsrA/SsrB
metabolic regulation
metabolism
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02724-23

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