High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transcriptomic and in vitro studiesResearch in context

High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transcriptomic and in vitro studiesResearch in context

Summary: Background: Systemic sclerosis-interstitial lung disease (SSc-ILD) is the leading cause of death in patients with SSc. There is an unmet need for predictive biomarkers to identify patients with SSc at risk of ILD. Previous studies have shown that interferon (IFN) pathways may play a role i...

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Bibliographic Details
Main Authors: Yehya Al-Adwi, Isabella Maria Atzeni, Berber Doornbos-van der Meer, Marcel John van der Leij, Rita Delphine Maiko Varkevisser, Bart-Jan Kroesen, Alja Stel, Wim Timens, Christiaan Tji Gan, Harry van Goor, Johanna Westra, Douwe Johannes Mulder
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:EBioMedicine
Subjects:
CXCL10
Biomarker
Inflammation
Fibrosis
ILD
Systemic sclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423004498

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