UbiProt: a database of ubiquitylated proteins

<p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseas...

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Main Authors: Kondratieva Ekaterina V, Shorina Anastasia S, Eremin Eugene V, Garcia Alejandro, Chernorudskiy Alexander L, Gainullin Murat R
Format: Article
Language:English
Published: BMC 2007-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/126
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author Kondratieva Ekaterina V
Shorina Anastasia S
Eremin Eugene V
Garcia Alejandro
Chernorudskiy Alexander L
Gainullin Murat R
author_facet Kondratieva Ekaterina V
Shorina Anastasia S
Eremin Eugene V
Garcia Alejandro
Chernorudskiy Alexander L
Gainullin Murat R
author_sort Kondratieva Ekaterina V
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied.</p> <p>Description</p> <p>To fill a general need for collecting and systematizing experimental data concerning ubiquitylation we have developed a new resource, UbiProt Database, a knowledgebase of ubiquitylated proteins. The database contains retrievable information about overall characteristics of a particular protein, ubiquitylation features, related ubiquitylation and de-ubiquitylation machinery and literature references reflecting experimental evidence of ubiquitylation. UbiProt is available at <url>http://ubiprot.org.ru</url> for free.</p> <p>Conclusion</p> <p>UbiProt Database is a public resource offering comprehensive information on ubiquitylated proteins. The resource can serve as a general reference source both for researchers in ubiquitin field and those who deal with particular ubiquitylated proteins which are of their interest. Further development of the UbiProt Database is expected to be of common interest for research groups involved in studies of the ubiquitin system.</p>
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spelling doaj.art-0c7e5b8eefda42319c95d627dcc1be152022-12-22T00:27:22ZengBMCBMC Bioinformatics1471-21052007-04-018112610.1186/1471-2105-8-126UbiProt: a database of ubiquitylated proteinsKondratieva Ekaterina VShorina Anastasia SEremin Eugene VGarcia AlejandroChernorudskiy Alexander LGainullin Murat R<p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied.</p> <p>Description</p> <p>To fill a general need for collecting and systematizing experimental data concerning ubiquitylation we have developed a new resource, UbiProt Database, a knowledgebase of ubiquitylated proteins. The database contains retrievable information about overall characteristics of a particular protein, ubiquitylation features, related ubiquitylation and de-ubiquitylation machinery and literature references reflecting experimental evidence of ubiquitylation. UbiProt is available at <url>http://ubiprot.org.ru</url> for free.</p> <p>Conclusion</p> <p>UbiProt Database is a public resource offering comprehensive information on ubiquitylated proteins. The resource can serve as a general reference source both for researchers in ubiquitin field and those who deal with particular ubiquitylated proteins which are of their interest. Further development of the UbiProt Database is expected to be of common interest for research groups involved in studies of the ubiquitin system.</p>http://www.biomedcentral.com/1471-2105/8/126
spellingShingle Kondratieva Ekaterina V
Shorina Anastasia S
Eremin Eugene V
Garcia Alejandro
Chernorudskiy Alexander L
Gainullin Murat R
UbiProt: a database of ubiquitylated proteins
BMC Bioinformatics
title UbiProt: a database of ubiquitylated proteins
title_full UbiProt: a database of ubiquitylated proteins
title_fullStr UbiProt: a database of ubiquitylated proteins
title_full_unstemmed UbiProt: a database of ubiquitylated proteins
title_short UbiProt: a database of ubiquitylated proteins
title_sort ubiprot a database of ubiquitylated proteins
url http://www.biomedcentral.com/1471-2105/8/126
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