UbiProt: a database of ubiquitylated proteins
<p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseas...
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Format: | Article |
Language: | English |
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BMC
2007-04-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/8/126 |
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author | Kondratieva Ekaterina V Shorina Anastasia S Eremin Eugene V Garcia Alejandro Chernorudskiy Alexander L Gainullin Murat R |
author_facet | Kondratieva Ekaterina V Shorina Anastasia S Eremin Eugene V Garcia Alejandro Chernorudskiy Alexander L Gainullin Murat R |
author_sort | Kondratieva Ekaterina V |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied.</p> <p>Description</p> <p>To fill a general need for collecting and systematizing experimental data concerning ubiquitylation we have developed a new resource, UbiProt Database, a knowledgebase of ubiquitylated proteins. The database contains retrievable information about overall characteristics of a particular protein, ubiquitylation features, related ubiquitylation and de-ubiquitylation machinery and literature references reflecting experimental evidence of ubiquitylation. UbiProt is available at <url>http://ubiprot.org.ru</url> for free.</p> <p>Conclusion</p> <p>UbiProt Database is a public resource offering comprehensive information on ubiquitylated proteins. The resource can serve as a general reference source both for researchers in ubiquitin field and those who deal with particular ubiquitylated proteins which are of their interest. Further development of the UbiProt Database is expected to be of common interest for research groups involved in studies of the ubiquitin system.</p> |
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format | Article |
id | doaj.art-0c7e5b8eefda42319c95d627dcc1be15 |
institution | Directory Open Access Journal |
issn | 1471-2105 |
language | English |
last_indexed | 2024-12-12T10:30:40Z |
publishDate | 2007-04-01 |
publisher | BMC |
record_format | Article |
series | BMC Bioinformatics |
spelling | doaj.art-0c7e5b8eefda42319c95d627dcc1be152022-12-22T00:27:22ZengBMCBMC Bioinformatics1471-21052007-04-018112610.1186/1471-2105-8-126UbiProt: a database of ubiquitylated proteinsKondratieva Ekaterina VShorina Anastasia SEremin Eugene VGarcia AlejandroChernorudskiy Alexander LGainullin Murat R<p>Abstract</p> <p>Background</p> <p>Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied.</p> <p>Description</p> <p>To fill a general need for collecting and systematizing experimental data concerning ubiquitylation we have developed a new resource, UbiProt Database, a knowledgebase of ubiquitylated proteins. The database contains retrievable information about overall characteristics of a particular protein, ubiquitylation features, related ubiquitylation and de-ubiquitylation machinery and literature references reflecting experimental evidence of ubiquitylation. UbiProt is available at <url>http://ubiprot.org.ru</url> for free.</p> <p>Conclusion</p> <p>UbiProt Database is a public resource offering comprehensive information on ubiquitylated proteins. The resource can serve as a general reference source both for researchers in ubiquitin field and those who deal with particular ubiquitylated proteins which are of their interest. Further development of the UbiProt Database is expected to be of common interest for research groups involved in studies of the ubiquitin system.</p>http://www.biomedcentral.com/1471-2105/8/126 |
spellingShingle | Kondratieva Ekaterina V Shorina Anastasia S Eremin Eugene V Garcia Alejandro Chernorudskiy Alexander L Gainullin Murat R UbiProt: a database of ubiquitylated proteins BMC Bioinformatics |
title | UbiProt: a database of ubiquitylated proteins |
title_full | UbiProt: a database of ubiquitylated proteins |
title_fullStr | UbiProt: a database of ubiquitylated proteins |
title_full_unstemmed | UbiProt: a database of ubiquitylated proteins |
title_short | UbiProt: a database of ubiquitylated proteins |
title_sort | ubiprot a database of ubiquitylated proteins |
url | http://www.biomedcentral.com/1471-2105/8/126 |
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