Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction

ObjectivesThe primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction.PatientThis 31-year-old male was diagnosed with MD and suspected autoimmune di...

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Bibliographic Details
Main Authors: Yurun Chen, Pengfei Zhao, Xin Ma, Tongxiang Diao, Lisheng Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1220162/full
Description
Summary:ObjectivesThe primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction.PatientThis 31-year-old male was diagnosed with MD and suspected autoimmune diseases.InterventionsImmunosuppressants and biological agents.Main outcomes measuresInner ear MRI images.ResultsChanges in the patient’s progress revealed that inner ear immune and inflammatory changes might induce EH, which may eventually turn into MD.ConclusionThis case is the first documented case of MRI revealing progressive changes from inflammatory response to endolymphatic hydrops in the inner ear. It shows the correlation between MD and inflammation visually. It is of great significance to reveal the pathogenesis of MD to further assist in the guidance of treatment decision making.
ISSN:1664-2295