ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors

ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors

Ataxia–telangiectasia mutated (ATM) functions as a key initiator and coordinator of DNA damage and cellular stress responses. ATM signaling pathways contain many downstream targets that regulate multiple important cellular processes, including DNA damage repair, apoptosis, cell cycle arrest, oxidati...

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Bibliographic Details
Main Authors: Sayaka Ueno, Tamotsu Sudo, Akira Hirasawa
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
hereditary tumors
ATM
DNA damage
redox homeostasis
tumor profiling
precision therapy
Online Access:https://www.mdpi.com/1422-0067/23/1/523

Internet

https://www.mdpi.com/1422-0067/23/1/523

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