Nephroprotective effect of AT-MSCs against cisplatin-induced EMT is improved by azilsartan via attenuating oxidative stress and TGF-β/Smad signaling
The nephrotoxicity of cisplatin (CIS) is a significant complication that challenges its clinical applicability. The epithelial to mesenchymal transition (EMT) may be included in the pathogenesis of CIS-evoked nephrotoxicity. Therefore, the current study aimed to evaluate, for the first time, the pos...
Main Authors: | Michael A. Fawzy, Olivia N. Beshay, Amany Abdlrehim Bekhit, Sara Mohamed Naguib Abdel-Hafez, Gaber El-Saber Batiha, Yousef A. Bin Jardan, Moustafa Fathy |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S075333222201486X |
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