BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)

Aim. To study different ways of development and combinational abilities of pathological changes common for bicuspid aortic valvulopathy. Material and methods. Totally 207 patients included, who had during previous 5 years been operated for progression of inherited aortic valve defect. The age varied...

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Main Authors: S. L. Dzemeshkevitch, V. A. Ivanov, E. R. Charchian, E. P. Evseev, Yu. V. Frolova, A. N. Lugovoy, S. V. Fedulova, V. V. Khovrin, A. A. Bukaeva, E. V. Zaklyazminskaya
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2014-05-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/69
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author S. L. Dzemeshkevitch
V. A. Ivanov
E. R. Charchian
E. P. Evseev
Yu. V. Frolova
A. N. Lugovoy
S. V. Fedulova
V. V. Khovrin
A. A. Bukaeva
E. V. Zaklyazminskaya
author_facet S. L. Dzemeshkevitch
V. A. Ivanov
E. R. Charchian
E. P. Evseev
Yu. V. Frolova
A. N. Lugovoy
S. V. Fedulova
V. V. Khovrin
A. A. Bukaeva
E. V. Zaklyazminskaya
author_sort S. L. Dzemeshkevitch
collection DOAJ
description Aim. To study different ways of development and combinational abilities of pathological changes common for bicuspid aortic valvulopathy. Material and methods. Totally 207 patients included, who had during previous 5 years been operated for progression of inherited aortic valve defect. The age varied from 17 to 75 years (median 49,6±0,9 y.), men to women — 3:1. Comorbidities included rheumatic fever in 33 (15,9%) patients and infectious endocarditis in the past in 45 (21,7%). In 111 (53,6%) patients aortic stenosis dominated and distension of ascending aorta — in 82 (39,6%) patients.Results. For most of patients mechanical prostheses were used and only for 12 — biological; 13 patients underwent valvulopastic or no any operation. One third of patients (31,9%) required a prosthesis of ascending aorta. Combinations of additional procedures (as aortic valve plastic or prosthesis, tricuspid plastic, left atrium plastic, septal defects sewing, coronary bypass grafting) were not unusual — in 57. In-hospital mortality reached 2,9%.Conclusion. Bicuspid aortic valve is a specific kind of valvulopathy, commonly combined with aortopathy. The development of this pathology is probably inherited. Clinical picture of the defect develops during time and its exacerbation might be accelerated by rheumathic fever and infectious endocarditis. Surgical treatment is effective.
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spelling doaj.art-0c8346f0fd0a456199f3830170afa27d2023-03-29T21:23:21Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202014-05-0105495410.15829/1560-4071-2014-5-49-5469BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)S. L. Dzemeshkevitch0V. A. Ivanov1E. R. Charchian2E. P. Evseev3Yu. V. Frolova4A. N. Lugovoy5S. V. Fedulova6V. V. Khovrin7A. A. Bukaeva8E. V. Zaklyazminskaya9FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, RussiaFSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, Russia.FSBI Petrovsky Russian Scientific Centre for Surgery of the Academy of Medical Sciences, Moscow, RussiaAim. To study different ways of development and combinational abilities of pathological changes common for bicuspid aortic valvulopathy. Material and methods. Totally 207 patients included, who had during previous 5 years been operated for progression of inherited aortic valve defect. The age varied from 17 to 75 years (median 49,6±0,9 y.), men to women — 3:1. Comorbidities included rheumatic fever in 33 (15,9%) patients and infectious endocarditis in the past in 45 (21,7%). In 111 (53,6%) patients aortic stenosis dominated and distension of ascending aorta — in 82 (39,6%) patients.Results. For most of patients mechanical prostheses were used and only for 12 — biological; 13 patients underwent valvulopastic or no any operation. One third of patients (31,9%) required a prosthesis of ascending aorta. Combinations of additional procedures (as aortic valve plastic or prosthesis, tricuspid plastic, left atrium plastic, septal defects sewing, coronary bypass grafting) were not unusual — in 57. In-hospital mortality reached 2,9%.Conclusion. Bicuspid aortic valve is a specific kind of valvulopathy, commonly combined with aortopathy. The development of this pathology is probably inherited. Clinical picture of the defect develops during time and its exacerbation might be accelerated by rheumathic fever and infectious endocarditis. Surgical treatment is effective.https://russjcardiol.elpub.ru/jour/article/view/69bicuspid aortic valveaortopathyvalve prosthesisthe genetics of connective tissue dysplasia
spellingShingle S. L. Dzemeshkevitch
V. A. Ivanov
E. R. Charchian
E. P. Evseev
Yu. V. Frolova
A. N. Lugovoy
S. V. Fedulova
V. V. Khovrin
A. A. Bukaeva
E. V. Zaklyazminskaya
BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
Российский кардиологический журнал
bicuspid aortic valve
aortopathy
valve prosthesis
the genetics of connective tissue dysplasia
title BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
title_full BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
title_fullStr BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
title_full_unstemmed BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
title_short BICUSPID AORTIC VALVE (A DEVELOPMENT OF INSIGHT INTO VALVULOPATHIES)
title_sort bicuspid aortic valve a development of insight into valvulopathies
topic bicuspid aortic valve
aortopathy
valve prosthesis
the genetics of connective tissue dysplasia
url https://russjcardiol.elpub.ru/jour/article/view/69
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