Minimally-Myelosuppressive Asparaginase-Containing Induction Regimen for Treatment of a Jehovah’s Witness with mutant IDH1/NPM1/NRAS Acute Myeloid Leukemia

Minimally-Myelosuppressive Asparaginase-Containing Induction Regimen for Treatment of a Jehovah’s Witness with mutant IDH1/NPM1/NRAS Acute Myeloid Leukemia

Treatment of patients with acute myeloid leukemia (AML) who do not wish to accept blood product transfusion, including Jehovah’s Witnesses, is extremely challenging. The use of conventional chemotherapy for induction of complete remission (CR) results in profound anemia and thrombocytopenia requirin...

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Bibliographic Details
Main Authors: Ashkan Emadi, Najeebah A. Bade, Brandi Stevenson, Zeba Singh
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Pharmaceuticals
Subjects:
acute myeloid leukemia (AML)
isocitrate dehydrogenase (IDH)
asparaginase
Online Access:http://www.mdpi.com/1424-8247/9/1/12

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