Sedative–Hypnotic Activity of the Water Extracts of <i>Coptidis Rhizoma</i> in Rodents

Sedative–Hypnotic Activity of the Water Extracts of <i>Coptidis Rhizoma</i> in Rodents

Many medicinal plants have been used in Asia for treating a variety of mental diseases, including insomnia and depression. However, their sedative–hypnotic effects and mechanisms have not been clarified yet. Accordingly, the objective of this study was to investigate the sedative–hypnotic effects of...

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Bibliographic Details
Main Authors: Hye-Young Joung, Minsook Ye, Miyoung Lee, Yunki Hong, Minji Kim, Kyung Soo Kim, Insop Shim
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Clocks & Sleep
Subjects:
<i>Coptidis Rhizoma</i>
sedative–hypnotic activity
GABA<sub>A</sub>–BZD receptor
5-HT<sub>2C</sub> receptor
arylalkylamine <i>N</i>-acetyltransterase (AANAT)
pentobarbital-induced sleep test
Online Access:https://www.mdpi.com/2624-5175/4/1/14

Internet

https://www.mdpi.com/2624-5175/4/1/14

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