Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation

Due to the increasingly strict word/character restrictions enforced by most scientific publications, we identified a need for a master document illustrating the “Scientific Methods” that may be applicable to the majority of observational and registry-based studies in hematopoietic cell transplantati...

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Main Authors: Abraham S. Kanate, Arnon Nagler, Bipin Savani
Format: Article
Language:English
Published: SAABRON PRESS 2019-12-01
Series:Clinical Hematology International
Subjects:
Online Access:https://www.atlantis-press.com/article/125926147/view
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author Abraham S. Kanate
Arnon Nagler
Bipin Savani
author_facet Abraham S. Kanate
Arnon Nagler
Bipin Savani
author_sort Abraham S. Kanate
collection DOAJ
description Due to the increasingly strict word/character restrictions enforced by most scientific publications, we identified a need for a master document illustrating the “Scientific Methods” that may be applicable to the majority of observational and registry-based studies in hematopoietic cell transplantation (HCT). The purpose of this study is to serve as a reference document that describes the data source, study endpoints and statistical analyses utilized most commonly in retrospective studies in HCT. To this end we compile, define and reference the methodology commonly used in HCT research. While it is recognized that the scientific methodology may periodically require updates due to the evolving landscape of transplant research, such as newer study endpoints and statistical methods, this manuscript describes frequently used methodologies.
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spelling doaj.art-0c88fd7d638643228748372e8e7844df2024-04-03T03:36:50ZengSAABRON PRESSClinical Hematology International2590-00482019-12-012110.2991/chi.d.191207.001Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell TransplantationAbraham S. KanateArnon NaglerBipin SavaniDue to the increasingly strict word/character restrictions enforced by most scientific publications, we identified a need for a master document illustrating the “Scientific Methods” that may be applicable to the majority of observational and registry-based studies in hematopoietic cell transplantation (HCT). The purpose of this study is to serve as a reference document that describes the data source, study endpoints and statistical analyses utilized most commonly in retrospective studies in HCT. To this end we compile, define and reference the methodology commonly used in HCT research. While it is recognized that the scientific methodology may periodically require updates due to the evolving landscape of transplant research, such as newer study endpoints and statistical methods, this manuscript describes frequently used methodologies.https://www.atlantis-press.com/article/125926147/viewHematopoietic cell transplantationScientific methodsStudy endpointsStudy definitions
spellingShingle Abraham S. Kanate
Arnon Nagler
Bipin Savani
Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
Clinical Hematology International
Hematopoietic cell transplantation
Scientific methods
Study endpoints
Study definitions
title Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
title_full Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
title_fullStr Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
title_full_unstemmed Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
title_short Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation
title_sort summary of scientific and statistical methods study endpoints and definitions for observational and registry based studies in hematopoietic cell transplantation
topic Hematopoietic cell transplantation
Scientific methods
Study endpoints
Study definitions
url https://www.atlantis-press.com/article/125926147/view
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AT arnonnagler summaryofscientificandstatisticalmethodsstudyendpointsanddefinitionsforobservationalandregistrybasedstudiesinhematopoieticcelltransplantation
AT bipinsavani summaryofscientificandstatisticalmethodsstudyendpointsanddefinitionsforobservationalandregistrybasedstudiesinhematopoieticcelltransplantation