Naringenin regulates production of matrix metalloproteinases in the knee-joint and primary cultured articular chondrocytes and alleviates pain in rat osteoarthritis model
Inflammation of cartilage is a primary symptom for knee-joint osteoarthritis. Matrix metalloproteinases (MMPs) are known to play an important role in the articular cartilage destruction related to osteoarthritis. Naringenin is a plant-derived flavonoid known for its anti-inflammatory properties. We...
Main Authors: | C.C. Wang, L. Guo, F.D. Tian, N. An, L. Luo, R.H. Hao, B. Wang, Z.H. Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
|
Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400603&lng=en&tlng=en |
Similar Items
-
Targeting Some Key Metalloproteinases by Nano-Naringenin and <i>Amphora coffeaeformis</i> as a Novel Strategy for Treatment of Osteoarthritis in Rats
by: Nema S. Shaban, et al.
Published: (2023-02-01) -
Naringenin modulates the metastasis of human prostate cancer cells by down regulating the matrix metalloproteinases -2/-9 via ROS/ERK1/2 pathways
by: Er-Jiang Lin, et al.
Published: (2014-09-01) -
Iron triggers the early stages of cartilage degeneration in vitro: The role of articular chondrocytes
by: A.V. Ferreira, et al.
Published: (2021-06-01) -
Naringenin attenuates inflammation and apoptosis of osteoarthritic chondrocytes via the TLR4/TRAF6/NF-κB pathway
by: Yan Wang, et al.
Published: (2023-11-01) -
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
by: Zhou Guo, et al.
Published: (2022-03-01)