A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia

A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia

Abstract Background Idiopathic interstitial pneumonia (IIP) is characterized by an increased rate of extracellular matrix (ECM) remodeling resulting in fibrosis. Acute exacerbations of IIP represent periods of increased disease activity, thus we hypothesized that ECM remodeling was altered during ac...

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Bibliographic Details
Main Authors: Jannie M. B. Sand, Yoshinori Tanino, Morten A. Karsdal, Takefumi Nikaido, Kenichi Misa, Yuki Sato, Ryuichi Togawa, Xintao Wang, Diana J. Leeming, Mitsuru Munakata
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Respiratory Research
Subjects:
Versican
Extracellular matrix
Biomarkers
Idiopathic interstitial pneumonia
Acute exacerbation
Online Access:http://link.springer.com/article/10.1186/s12931-018-0779-y

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