Primary breast tumor induced extracellular matrix remodeling in premetastatic lungs
Abstract The premetastatic niche hypothesis proposes an active priming of the metastatic site by factors secreted from the primary tumor prior to the arrival of the first cancer cells. We investigated several extracellular matrix (ECM) structural proteins, ECM degrading enzymes, and ECM processing p...
Main Authors: | Ruoqing Cai, Caitlin M. Tressler, Menglin Cheng, Kanchan Sonkar, Zheqiong Tan, Santosh Kumar Paidi, Vinay Ayyappan, Ishan Barman, Kristine Glunde |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-45832-7 |
Similar Items
-
Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodelling
by: Sara F.F. Almeida, et al.
Published: (2023-11-01) -
Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment
by: Braeden Medeiros, et al.
Published: (2020-01-01) -
Cellular and molecular characteristics of the premetastatic niches
by: Hongfei Liu, et al.
Published: (2023-10-01) -
The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche
by: Laurence Blavier, et al.
Published: (2023-05-01) -
The Premetastatic Lymph Node Niche in Gynecologic Cancer
by: Georgia Karpathiou, et al.
Published: (2023-02-01)