Intravitreal Injection of Long-Acting Pegylated Granulocyte Colony-Stimulating Factor Provides Neuroprotective Effects via Antioxidant Response in a Rat Model of Traumatic Optic Neuropathy

Intravitreal Injection of Long-Acting Pegylated Granulocyte Colony-Stimulating Factor Provides Neuroprotective Effects via Antioxidant Response in a Rat Model of Traumatic Optic Neuropathy

Traumatic optic neuropathy (TON) may cause severe visual loss following direct or indirect head trauma which may result in optic nerve injuries and therefore contribute to the subsequent loss of retinal ganglion cells by inflammatory mediators and reactive oxygen species (ROS). Granulocyte colony-st...

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Bibliographic Details
Main Authors: Chin-Te Huang, Yao-Tseng Wen, Tushar Dnyaneshwar Desai, Rong-Kung Tsai
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antioxidants
Subjects:
traumatic optic neuropathy
oxidative stress
neuroinflammation
neurodegeneration
pegylated granulocyte colony-stimulating factor
microglia
Online Access:https://www.mdpi.com/2076-3921/10/12/1934

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https://www.mdpi.com/2076-3921/10/12/1934

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