Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature

Sarcoidosis is a multisystem granulomatous disorder of unknown etiology, primarily affecting the intrathoracic lymph node and the lung. The endobronchial involvement in sarcoidosis is not uncommon and may appear as nodules, cobblestoning, erythema, or plaque, but presentation as an endobronchial mas...

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Main Authors: Deependra Kumar Rai, Prashant Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Family Medicine and Primary Care
Subjects:
Online Access:http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3399;epage=3401;aulast=Rai
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author Deependra Kumar Rai
Prashant Kumar
author_facet Deependra Kumar Rai
Prashant Kumar
author_sort Deependra Kumar Rai
collection DOAJ
description Sarcoidosis is a multisystem granulomatous disorder of unknown etiology, primarily affecting the intrathoracic lymph node and the lung. The endobronchial involvement in sarcoidosis is not uncommon and may appear as nodules, cobblestoning, erythema, or plaque, but presentation as an endobronchial mass has been rarely described. We report here a 50-year-old gentleman who presented with nonproductive cough and dyspnea on exertion. Video bronchoscopy revealed a polypoid mass in the right lower lobe bronchus occluding the posterior basal segment, and bronchial biopsy revealed noncaseating granulomatous inflammation. Bronchoalveolar lavage (BAL) fluid was negative for tuberculosis, fungal infection, and malignancy. Mantoux test was negative, and serum angiotensin-converting enzyme was elevated. The diagnosis of sarcoidosis was made, and the patient was started on an oral corticosteroid. After treatment, the patient showed significant improvement in symptoms. This case report highlights a rare presentation of sarcoidosis as an endobronchial mass lesion. It is important to take a biopsy to differentiate from other common causes of endobronchial mass, such as malignancy and, rarely, tuberculosis. Sarcoidosis should be considered in a differential of the endobronchial mass lesion.
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spelling doaj.art-0c974aa46d34452ea172466cbf429d842024-04-01T06:00:31ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632023-01-0112123399340110.4103/jfmpc.jfmpc_255_23Sarcoidosis present as endobronchial lung mass: A rare case report with review of literatureDeependra Kumar RaiPrashant KumarSarcoidosis is a multisystem granulomatous disorder of unknown etiology, primarily affecting the intrathoracic lymph node and the lung. The endobronchial involvement in sarcoidosis is not uncommon and may appear as nodules, cobblestoning, erythema, or plaque, but presentation as an endobronchial mass has been rarely described. We report here a 50-year-old gentleman who presented with nonproductive cough and dyspnea on exertion. Video bronchoscopy revealed a polypoid mass in the right lower lobe bronchus occluding the posterior basal segment, and bronchial biopsy revealed noncaseating granulomatous inflammation. Bronchoalveolar lavage (BAL) fluid was negative for tuberculosis, fungal infection, and malignancy. Mantoux test was negative, and serum angiotensin-converting enzyme was elevated. The diagnosis of sarcoidosis was made, and the patient was started on an oral corticosteroid. After treatment, the patient showed significant improvement in symptoms. This case report highlights a rare presentation of sarcoidosis as an endobronchial mass lesion. It is important to take a biopsy to differentiate from other common causes of endobronchial mass, such as malignancy and, rarely, tuberculosis. Sarcoidosis should be considered in a differential of the endobronchial mass lesion.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3399;epage=3401;aulast=Raibronchoscopylung massmalignancysarcoidosis
spellingShingle Deependra Kumar Rai
Prashant Kumar
Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
Journal of Family Medicine and Primary Care
bronchoscopy
lung mass
malignancy
sarcoidosis
title Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
title_full Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
title_fullStr Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
title_full_unstemmed Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
title_short Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature
title_sort sarcoidosis present as endobronchial lung mass a rare case report with review of literature
topic bronchoscopy
lung mass
malignancy
sarcoidosis
url http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3399;epage=3401;aulast=Rai
work_keys_str_mv AT deependrakumarrai sarcoidosispresentasendobronchiallungmassararecasereportwithreviewofliterature
AT prashantkumar sarcoidosispresentasendobronchiallungmassararecasereportwithreviewofliterature