PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients

PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients

Abstract The PALB2 gene is a breast cancer (BC) and ovarian cancer (OC) predisposition gene involved in the homologous recombination repair pathway. However, the prevalence and clinicopathological association of PALB2 pathogenic/likely pathogenic (PV/LPV) variants in Middle East is still not fully e...

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Bibliographic Details
Main Authors:	Abdul K. Siraj, Rong Bu, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Ingrid G. Victoria, Ismail A. Al-Badawi, Asma Tulbah, Fouad Al-Dayel, Dahish Ajarim, Khawla S. Al-Kuraya
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-05-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-34693-9

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