Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs

Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs

Diabetes mellitus (DM) in humans has recently been associated with altered intestinal microbiota. The consequences of intestinal dysbiosis, such as increased intestinal permeability and altered microbial metabolites, are suspected to contribute to the host inflammatory state and peripheral insulin r...

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Bibliographic Details
Main Authors: Albert E. Jergens, Blake C. Guard, Alana Redfern, Giacomo Rossi, Jonathan P. Mochel, Rachel Pilla, Lawrance Chandra, Yeon-Jung Seo, Joerg M. Steiner, Jonathan Lidbury, Karin Allenspach, Jan Suchodolski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Veterinary Science
Subjects:
bile acids
diabetes mellitus
microbiota
lipopolysaccharide
dog
T2DM
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2019.00199/full

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