<i>Lactobacillus paracasei</i> CCFM1229 and <i>Lactobacillus rhamnosus</i> CCFM1228 Alleviated Depression- and Anxiety-Related Symptoms of Chronic Stress-Induced Depression in Mice by Regulating Xanthine Oxidase Activity in the Brain

<i>Lactobacillus paracasei</i> CCFM1229 and <i>Lactobacillus rhamnosus</i> CCFM1228 Alleviated Depression- and Anxiety-Related Symptoms of Chronic Stress-Induced Depression in Mice by Regulating Xanthine Oxidase Activity in the Brain

Depression is a common mood disorder that affects around 350 million people worldwide. We studied the effect of supplementation with <i>Lactobacillus</i> strains for the treatment of depression. Except for control group (<i>n</i> = 8), C57BL/6J mice were treated with <i>...

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Bibliographic Details
Main Authors: Mengshu Xu, Peijun Tian, Huiyue Zhu, Renying Zou, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Nutrients
Subjects:
probiotic
gut–brain axis
depression
microbiota
purine metabolism
xanthine oxidase
Online Access:https://www.mdpi.com/2072-6643/14/6/1294

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