Rituximab in Adult –Onset Still’s Disease: Case Report
Summary: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. It is characterized by high grade fever, skin rash, arthritis, leukocytosis, increased ESR, CRP and liver enzyme levels and high levels of ferritin. The treatment of AOSD includes NSAIDs, steroi...
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| Format: | Article |
| Language: | fas |
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Shahid Sadoughi University of Medical Sciences
2009-01-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
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| Online Access: | http://85.185.157.11:6280/jssu/browse.php?a_id=610&slc_lang=en&sid=1&ftxt=1 |
| _version_ | 1818787390066524160 |
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| author | G Mehrpoor MB Owlia |
| author_facet | G Mehrpoor MB Owlia |
| author_sort | G Mehrpoor |
| collection | DOAJ |
| description | Summary: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. It is characterized by high grade fever, skin rash, arthritis, leukocytosis, increased ESR, CRP and liver enzyme levels and high levels of ferritin. The treatment of AOSD includes NSAIDs, steroids, and disease-modifying antirheumatic drugs (DMARDs). Recently biologic agents have been used for treatment of some rheumatologic disorders. Rituximab(MabThera), an anti-CD20 monoclonal antibody is one of the biologic agents which is used by only a few researchers for treatment of refractory AOSD. Herein, we describe a 23 year old woman, who was treated with Rituximab ,three years after diagnosis of AOSD .She did not respond to Metotroxate and Cellcept .After administration of Rituximab, clinical and laboratory remission was achieved . |
| first_indexed | 2024-12-18T14:07:00Z |
| format | Article |
| id | doaj.art-0c9c0bc153894d88b19a1b1c6a3d2349 |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-12-18T14:07:00Z |
| publishDate | 2009-01-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-0c9c0bc153894d88b19a1b1c6a3d23492022-12-21T21:05:13ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332009-01-011649299Rituximab in Adult –Onset Still’s Disease: Case ReportG MehrpoorMB OwliaSummary: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. It is characterized by high grade fever, skin rash, arthritis, leukocytosis, increased ESR, CRP and liver enzyme levels and high levels of ferritin. The treatment of AOSD includes NSAIDs, steroids, and disease-modifying antirheumatic drugs (DMARDs). Recently biologic agents have been used for treatment of some rheumatologic disorders. Rituximab(MabThera), an anti-CD20 monoclonal antibody is one of the biologic agents which is used by only a few researchers for treatment of refractory AOSD. Herein, we describe a 23 year old woman, who was treated with Rituximab ,three years after diagnosis of AOSD .She did not respond to Metotroxate and Cellcept .After administration of Rituximab, clinical and laboratory remission was achieved .http://85.185.157.11:6280/jssu/browse.php?a_id=610&slc_lang=en&sid=1&ftxt=1Adult-onset Still’s diseaseBiologic treatmentRituximab |
| spellingShingle | G Mehrpoor MB Owlia Rituximab in Adult –Onset Still’s Disease: Case Report Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Adult-onset Still’s disease Biologic treatment Rituximab |
| title | Rituximab in Adult –Onset Still’s Disease: Case Report |
| title_full | Rituximab in Adult –Onset Still’s Disease: Case Report |
| title_fullStr | Rituximab in Adult –Onset Still’s Disease: Case Report |
| title_full_unstemmed | Rituximab in Adult –Onset Still’s Disease: Case Report |
| title_short | Rituximab in Adult –Onset Still’s Disease: Case Report |
| title_sort | rituximab in adult onset still s disease case report |
| topic | Adult-onset Still’s disease Biologic treatment Rituximab |
| url | http://85.185.157.11:6280/jssu/browse.php?a_id=610&slc_lang=en&sid=1&ftxt=1 |
| work_keys_str_mv | AT gmehrpoor rituximabinadultonsetstillsdiseasecasereport AT mbowlia rituximabinadultonsetstillsdiseasecasereport |