Analytic pipelines to assess the relationship between immune response and germline genetics in human tumors

Analytic pipelines to assess the relationship between immune response and germline genetics in human tumors

Summary: Germline genetic variants modulate human immune response. We present analytical pipelines for assessing the contribution of hosts’ genetic background to the immune landscape of solid tumors using harmonized data from more than 9,000 patients in The Cancer Genome Atlas (TCGA). These include...

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Bibliographic Details
Main Authors: Rosalyn W. Sayaman, Mohamad Saad, Carolina Heimann, Donglei Hu, Khalid Kunji, Jessica Roelands, Denise M. Wolf, Scott Huntsman, Michele Ceccarelli, Vésteinn Thorsson, Elad Ziv, Davide Bedognetti
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:STAR Protocols
Subjects:
Bioinformatics
Cancer
Genetics
Genomics
Immunology
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672200689X

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