Csn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae

Csn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae

Abstract Csn5 is subunit 5 of the COP9 signalosome (CSN), but the mechanism by which it strictly controls the pathogenicity of pathogenic fungi through autophagy remains unclear. Here, we found that Csn5 deficiency attenuated pathogenicity and enhanced autophagy in Magnaporthe oryzae. MoCSN5 knockou...

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Main Authors: Zi-Fang Shen, Lin Li, Jing-Yi Wang, Jian Liao, Yun-Ran Zhang, Xue-Ming Zhu, Zi-He Wang, Jian-Ping Lu, Xiao-Hong Liu, Fu-Cheng Lin
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cell Communication and Signaling
Subjects:
COP9 signalosome
Csn5
Autophagy
Ubiquitination
Pathogenicity
Rice blast fungus
Online Access:https://doi.org/10.1186/s12964-024-01598-7

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