Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a

Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a

Osteosarcoma (OS) has a high incidence, malignity, and frequency of recurrence and metastasis. In this study, we aimed to explore the potential anti-cancer effects of Astragalus polysaccharides (APS) on human OS MG63 cells as well as underlying mechanisms. Viability of MG63 cells was assessed by CCK...

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Bibliographic Details
Main Authors:	Yanchen Chu, Yuan Fang, Jingwei Chi, Jing Li, Dongyang Zhang, Yunwen Zou, Zhijie Wang
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2018-11-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Osteosarcoma Astragalus polysaccharides Anti-tumor microRNA-133a JNK
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200610&lng=en&tlng=en

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