Piperazine Derivative Stabilizes Actin Filaments in Primary Fibroblasts and Binds G-Actin In Silico

Piperazine Derivative Stabilizes Actin Filaments in Primary Fibroblasts and Binds G-Actin In Silico

Alzheimer’s disease (AD) is characterized by synaptic dysfunction, which is expressed through the loss of dendritic spines and changes in their morphology. Pharmacological compounds that are able to protect spines in the AD brain are suggested to be novel drugs that would be able to slow down the di...

Full description

Bibliographic Details
Main Authors: Nikita Zernov, Viktor Ghamaryan, Ani Makichyan, Daria Melenteva, Lernik Hunanyan, Elena Popugaeva
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Current Issues in Molecular Biology
Subjects:
piperazine
actin
neuroprotection
Online Access:https://www.mdpi.com/1467-3045/44/11/353

Similar Items

Similar Items