Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study
OBJECTIVES: Shift work is associated with metabolic disorders as it disturbs circadian rhythms. However, the potential association of shift work with knee osteoarthritis (KOA), a metabolic-related disease, has not been confirmed. The objective of this study was to quantify the association of shift w...
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| Format: | Article |
| Language: | English |
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Nordic Association of Occupational Safety and Health (NOROSH)
2020-03-01
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| Series: | Scandinavian Journal of Work, Environment & Health |
| Subjects: | |
| Online Access: |
https://www.sjweh.fi/show_abstract.php?abstract_id=3861
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| _version_ | 1818640828778676224 |
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| author | Min Zhou Shijie Yang Yanjun Guo Dongming Wang Weihong Qiu Bin Wang Ge Mu Limin Cao Zhuang Zhang Weihong Chen |
| author_facet | Min Zhou Shijie Yang Yanjun Guo Dongming Wang Weihong Qiu Bin Wang Ge Mu Limin Cao Zhuang Zhang Weihong Chen |
| author_sort | Min Zhou |
| collection | DOAJ |
| description | OBJECTIVES: Shift work is associated with metabolic disorders as it disturbs circadian rhythms. However, the potential association of shift work with knee osteoarthritis (KOA), a metabolic-related disease, has not been confirmed. The objective of this study was to quantify the association of shift work with the risk of KOA. METHODS: This retrospective cohort study comprising 13 741 retired workers from the Dongfeng Motor Corporation. KOA was defined by knee pain and clinical X-ray radiographs. Occupational history, including job description and shift work, was collected from face-to-face interviews using questionnaires. Cox proportional hazards regression models were used to estimate exposure–response relationships. RESULTS: During the 590 085 person-years of follow-up, a total of 847 cases of KOA (incidence of KOA was 143.5 per 100 000 person-years) were identified. After adjusting for potential confounders, shift work was independently associated with an elevated risk of KOA [hazard ratio (HR) 1.19, 95% confidence interval 1.03–1.36]. Compared with daytime workers, the risk of KOA increased with prolonged periods of shift work; the HR of KOA for participants with 1–9 years, 10–19 years, and ≥20 years shift work were 1.03 (95% CI 0.84–1.26), 1.19 (95% CI 0.98–1.46), and 1.42 (95% CI 1.15–1.76), respectively. The HR for KOA associated with shift work gradually decreased as the period after finishing shift work increased. CONCLUSION: Our results indicated that shift work could be an independent risk factor for KOA. |
| first_indexed | 2024-12-16T23:17:29Z |
| format | Article |
| id | doaj.art-0cb1a1d4996f4930ad08f4c21ae2408f |
| institution | Directory Open Access Journal |
| issn | 0355-3140 1795-990X |
| language | English |
| last_indexed | 2024-12-16T23:17:29Z |
| publishDate | 2020-03-01 |
| publisher | Nordic Association of Occupational Safety and Health (NOROSH) |
| record_format | Article |
| series | Scandinavian Journal of Work, Environment & Health |
| spelling | doaj.art-0cb1a1d4996f4930ad08f4c21ae2408f2022-12-21T22:12:15ZengNordic Association of Occupational Safety and Health (NOROSH)Scandinavian Journal of Work, Environment & Health0355-31401795-990X2020-03-0146215216010.5271/sjweh.38613861Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort studyMin ZhouShijie YangYanjun GuoDongming WangWeihong QiuBin WangGe MuLimin CaoZhuang ZhangWeihong Chen0School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.OBJECTIVES: Shift work is associated with metabolic disorders as it disturbs circadian rhythms. However, the potential association of shift work with knee osteoarthritis (KOA), a metabolic-related disease, has not been confirmed. The objective of this study was to quantify the association of shift work with the risk of KOA. METHODS: This retrospective cohort study comprising 13 741 retired workers from the Dongfeng Motor Corporation. KOA was defined by knee pain and clinical X-ray radiographs. Occupational history, including job description and shift work, was collected from face-to-face interviews using questionnaires. Cox proportional hazards regression models were used to estimate exposure–response relationships. RESULTS: During the 590 085 person-years of follow-up, a total of 847 cases of KOA (incidence of KOA was 143.5 per 100 000 person-years) were identified. After adjusting for potential confounders, shift work was independently associated with an elevated risk of KOA [hazard ratio (HR) 1.19, 95% confidence interval 1.03–1.36]. Compared with daytime workers, the risk of KOA increased with prolonged periods of shift work; the HR of KOA for participants with 1–9 years, 10–19 years, and ≥20 years shift work were 1.03 (95% CI 0.84–1.26), 1.19 (95% CI 0.98–1.46), and 1.42 (95% CI 1.15–1.76), respectively. The HR for KOA associated with shift work gradually decreased as the period after finishing shift work increased. CONCLUSION: Our results indicated that shift work could be an independent risk factor for KOA. https://www.sjweh.fi/show_abstract.php?abstract_id=3861 metabolic disorderoccupational healthcohort studyworkerchinashift workcircadian rhythmshift workershift rotationknee osteoarthritisretrospective cohort studychinese worker |
| spellingShingle | Min Zhou Shijie Yang Yanjun Guo Dongming Wang Weihong Qiu Bin Wang Ge Mu Limin Cao Zhuang Zhang Weihong Chen Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study Scandinavian Journal of Work, Environment & Health metabolic disorder occupational health cohort study worker china shift work circadian rhythm shift worker shift rotation knee osteoarthritis retrospective cohort study chinese worker |
| title | Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study |
| title_full | Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study |
| title_fullStr | Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study |
| title_full_unstemmed | Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study |
| title_short | Shift work and the risk of knee osteoarthritis among Chinese workers: a retrospective cohort study |
| title_sort | shift work and the risk of knee osteoarthritis among chinese workers a retrospective cohort study |
| topic | metabolic disorder occupational health cohort study worker china shift work circadian rhythm shift worker shift rotation knee osteoarthritis retrospective cohort study chinese worker |
| url |
https://www.sjweh.fi/show_abstract.php?abstract_id=3861
|
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